CAS 288-32-4|CAS 1834623|imidazole|1H-imidazole|1,3-Diazacyclopenta-2,4-diene|1H-Imidazole|1,3-Diaza-2,4-Cyclopentadiene|Miazole|glyoxaline (archaic)|IMIDAZOLE|1,3-Diazole|Glyoxalin|Iminazole|Imutex...

基本信息

化学结构

分子式

C₃H₄N₂

分子量

68.07726

精确质量

68.03744814

电荷

InChI

InChI=1S/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5)

InChIKey

RAXXELZNTBOGNW-UHFFFAOYSA-N

Canonic Smiles

c1ncc[nH]1

Isomeric Smiles

n1c[nH]cc1

计算属性

JChem

LogD (pH = 7.4)

-0.24

LogD (pH = 5.5)

-0.70

Log P

-0.15

可自由旋转的化学键

质子供体

质子受体

里宾斯基五规则

true

Acid pKa

6.97

极化表面积

28.68

极化性

6.56

摩尔折射率

19.01

LOG S

-0.10

数据来源

名称和标识

别名

1H-Imidazole1,3-Diazacyclopenta-2,4-dieneMiazole1,3-Diaza-2,4-CyclopentadieneIMIDAZOLE1,3-Diazoleglyoxaline (archaic)GlyoxalinIminazoleImutex咪唑Glyoxaline甘恶啉Imidazole1,3-二氮杂-2,4-环戊二烯3-Azapyrrole1H-Imidazole甘恶啉溶液Imidazole buffer SolutionGlyoxaline solutionImidazole solutionOndansetron impurity E (Ph Eur)1,3-diaza-2,4-cyclopentadieneiminazole1,3-DiazoleIMD1,3-diazoleN,N'-1,2-ethenediylmethanimidamideGlyoxalineimidazolepyrro[b]monazolemiazoleN,N'-vinyleneformamidine1H-imidazole1H-imidazoleHimImidazolImidazole

IUPAC传统名

imidazole Him

IUPAC标准名

1H-imidazole

名称和标识

数据登录号

化合物性质

安全信息

Corrosive/Harmful/Teratogenic/Store under Argon

S:26-27/28-36/37/39-46-64

化合物性质

分子相关蛋白质

暂无数据

点击上传数据

分子相关蛋白质

分子图谱

暂无数据

点击上传数据

描述信息

MP Biomedicals

02102031

Histamine Antagonist
Highly Purified: 99+%

02102033

Slightly off-white, crystalline powder.
Purity: 99%
Excellent for buffer use in pH range 6.2-7.8. The m.p. of this product is 89-91°C. Please note many other "dealers" offer inferior imidazole with m.p. 87-91°C.

02194829

Molecular Biology Reagent
Purity: 99+%
Histamine Antagonist.
Useful pH range: 6.2-7.8

Wikipedia

Imidazole

Sigma Aldrich

I2399

Application
特别适用于 pH 6.2-7.8 范围内的缓冲液
包装
100, 500 g in glass bottle

I0125

Application
特别适用于 pH 6.2-7.8 范围内的缓冲液
包装
10, 25, 100, 500 g in glass bottle
5 kg in poly drum

I0250

Application
特别适用于 pH 6.2-7.8 范围内的缓冲液

I5513

Application
特别适用于 pH 6.2-7.8 范围内的缓冲液

I202

Application
可用作抗代谢物和组胺抑制剂。还可用于合成。
特别适用于 pH 6.2-7.8 范围内的缓冲液
包装
1, 5, 25 g in glass bottle
2 kg in poly bottle
100, 500 g in poly bottle
5 kg in poly drum
法律信息
ReagentPlus 注册商标 Sigma-Aldrich Co. LLC
Protocols & Applications
Metal Organic Framework Linkers Technology Spotlight

56749

Application
特别适用于 pH 6.2-7.8 范围内的缓冲液
Other Notes
Buffer for assay of horseradish peroxidase1

56748

Application
特别适用于 pH 6.2-7.8 范围内的缓冲液
Other Notes
Review: As RNase model1

49128

Application
特别适用于 pH 6.2-7.8 范围内的缓冲液

56745

Application
特别适用于 pH 6.2-7.8 范围内的缓冲液
Other Notes
Kinetic investigations with pig kidney Na+,K+-ATPase, by stopped-flow fluorimetry1,2

02739

Application
特别适用于 pH 6.2-7.8 范围内的缓冲液

56750

Application
特别适用于 pH 6.2-7.8 范围内的缓冲液
Other Notes
用于滴定天冬氨酸和谷氨酸1

15-0020

Application
特别适用于 pH 6.2-7.8 范围内的缓冲液

TRC

I350200

Imidazole is a versatile heterocycle used in the preparation of various biologically active compounds such as the amino acid histidine and is present in many antifungal medication. It is also used extensively as a corrosion inhibitor on transition metals

ChEBI

CHEBI:16069

An imidazole tautomer which has the migrating hydrogen at position 1.

描述信息

参考文献

PubChem文献

数据源提供

• Arispe, N. et al.: Biophys. J., 95, 4879 (2008)

• Troesken, E.R. et al.: Endo. Res., 30, 387 (2008)

• Otmacic Curkovic, H. et al.: Corr. Sci., 51, 2342 (2008)

• For use in: silylation of 1,3-diketones, see Hexamethyldisilazane, A15139; introduction of the TBDMS and TBDPS groups; see: tert-Butyldimethylchlorosilane, A13064, and tert-Butyldiphenylchlorosilane, A12721, respectively.

• With 2 moles of an aroyl halide gives, after hydrolysis, good yields of 2-aroylimidazoles: Synthesis, 675 (1978).

• Nucleophilic catalyst for many acylation and silylation reactions, compare 4-(Dimethylamino)pyridine, A13016.

• In combination with triphenylphosphine and iodine, vic-diols are converted to alkenes: Synthesis, 469 (1979), and alcohols to alkyl iodides: Synth. Commun., 20, 1473 (1990).

参考文献

生物活性

PubChem BioAssay

生物活性

名称和标识

别名

IUPAC传统名

imidazole Him

IUPAC标准名

1H-imidazole

描述信息

MP Biomedicals

02102031

Histamine Antagonist
Highly Purified: 99+%

02102033

02194829

Molecular Biology Reagent
Purity: 99+%
Histamine Antagonist.
Useful pH range: 6.2-7.8

Wikipedia

Imidazole

Sigma Aldrich

I2399

Application
特别适用于 pH 6.2-7.8 范围内的缓冲液
包装
100, 500 g in glass bottle

I0125

Application
特别适用于 pH 6.2-7.8 范围内的缓冲液
包装
10, 25, 100, 500 g in glass bottle
5 kg in poly drum

I0250

Application
特别适用于 pH 6.2-7.8 范围内的缓冲液

I5513

Application
特别适用于 pH 6.2-7.8 范围内的缓冲液

I202

56749

Application
特别适用于 pH 6.2-7.8 范围内的缓冲液
Other Notes
Buffer for assay of horseradish peroxidase1

56748

Application
特别适用于 pH 6.2-7.8 范围内的缓冲液
Other Notes
Review: As RNase model1

49128

Application
特别适用于 pH 6.2-7.8 范围内的缓冲液

56745

Application
特别适用于 pH 6.2-7.8 范围内的缓冲液
Other Notes
Kinetic investigations with pig kidney Na+,K+-ATPase, by stopped-flow fluorimetry1,2

02739

Application
特别适用于 pH 6.2-7.8 范围内的缓冲液

56750

Application
特别适用于 pH 6.2-7.8 范围内的缓冲液
Other Notes
用于滴定天冬氨酸和谷氨酸1

15-0020

Application
特别适用于 pH 6.2-7.8 范围内的缓冲液

TRC

I350200

ChEBI

CHEBI:16069

An imidazole tautomer which has the migrating hydrogen at position 1.

参考文献

PubChem文献

数据源提供

• Arispe, N. et al.: Biophys. J., 95, 4879 (2008)

• Troesken, E.R. et al.: Endo. Res., 30, 387 (2008)

• Otmacic Curkovic, H. et al.: Corr. Sci., 51, 2342 (2008)

• With 2 moles of an aroyl halide gives, after hydrolysis, good yields of 2-aroylimidazoles: Synthesis, 675 (1978).

• Nucleophilic catalyst for many acylation and silylation reactions, compare 4-(Dimethylamino)pyridine, A13016.

• In combination with triphenylphosphine and iodine, vic-diols are converted to alkenes: Synthesis, 469 (1979), and alcohols to alkyl iodides: Synth. Commun., 20, 1473 (1990).

生物活性

PubChem BioAssay

化合物性质

安全信息

Corrosive/Harmful/Teratogenic/Store under Argon

S:26-27/28-36/37/39-46-64

分子相关蛋白质

暂无数据

点击上传数据

化合物信息

ID:89483