CAS 939-26-4|(2-naphthyl)bromomethane|2-(bromomethyl)naphthalene|2-(Bromomethyl)naphthalene 96%|2-(溴甲基)萘|2-(bromomethyl)naphthalene|2-(Bromomethyl)naphthalene|2-Naphthylmethyl bromide

基本信息

化学结构

分子式

C₁₁H₉Br

分子量

221.09316

精确质量

219.98876229

电荷

InChI

InChI=1S/C11H9Br/c12-8-9-5-6-10-3-1-2-4-11(10)7-9/h1-7H,8H2

InChIKey

RUHJZSZTSCSTCC-UHFFFAOYSA-N

Canonic Smiles

BrCc1ccc2c(c1)cccc2

Isomeric Smiles

BrCc1cc2c(cc1)cccc2

计算属性

JChem

质子受体

质子供体

LogD (pH = 5.5)

3.73546

LogD (pH = 7.4)

3.73546

Log P

3.73546

摩尔折射率

55.3586

极化性

22.21318

极化表面积

0.0

可自由旋转的化学键

里宾斯基五规则

true

数据来源

名称和标识

IUPAC传统名

(2-naphthyl)bromomethane

IUPAC标准名

2-(bromomethyl)naphthalene

别名

2-(Bromomethyl)naphthalene 96%2-(bromomethyl)naphthalene2-Naphthylmethyl bromide2-(Bromomethyl)naphthalene2-(溴甲基)萘

名称和标识

数据登录号

CAS号

939-26-4

EC号

213-359-5

Beilstein号

636546

PubChem SID

2485055624848601162075754

MDL号

MFCD00004123

PubChem CID

70320

数据登录号

化合物性质

分子相关蛋白质

暂无数据

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分子图谱

暂无数据

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描述信息

Sigma Aldrich

143677

包装
5, 25, 100 g in glass bottle

描述信息

参考文献

PubChem文献

数据源提供

• NAP protection of amino groups and other N functions has also been reported. Cleavage was effected under mild condtions with DDQ: Synlett, 2065 (2003).

• Primary or secondary OH groups can be protected as 2-naphthylmethyl (NAP) ethers, e.g. with NaH in DMF. The NAP ether is stable to dilute aqueous HCl or NaOH, but is cleanly hydrogenolyzed with Pd/C; preferential cleavage in the presence of a benzyl ether can be achieved in high yield: J. Org. Chem., 63, 4172 (1998). NAP protection has been utilized in carbohydrate synthesis where stability to 4% TFA in CHCl₃, hot 80% AcOH, SnCl₂/AgOTf, or HCl/EtOH were demonstrated, conditions under which the 4-methoxybenzyl (PMB) group is cleaved; both NAP and PMB groups are efficiently cleaved with DDQ: Tetrahedron Lett., 41, 169 (2000).

参考文献

生物活性

PubChem BioAssay

生物活性

名称和标识

IUPAC传统名

(2-naphthyl)bromomethane

IUPAC标准名

2-(bromomethyl)naphthalene

别名

2-(Bromomethyl)naphthalene 96%2-(bromomethyl)naphthalene2-Naphthylmethyl bromide2-(Bromomethyl)naphthalene2-(溴甲基)萘

数据登录号

CAS号

939-26-4

EC号

213-359-5

Beilstein号

636546

PubChem SID

2485055624848601162075754

MDL号

MFCD00004123

PubChem CID

70320

描述信息

Sigma Aldrich

143677

包装
5, 25, 100 g in glass bottle

参考文献

PubChem文献

数据源提供

• NAP protection of amino groups and other N functions has also been reported. Cleavage was effected under mild condtions with DDQ: Synlett, 2065 (2003).

生物活性

PubChem BioAssay

化合物性质

化合物信息

ID:88856