化合物信息

DB01997 

Drug information: experimental

OR6862T 

A more potent inhibitor of rat cerebellar nitric oxide synthase than 7-nitroindazole.Harmful to reproduction

B2050 

Biochem/physiol Actions
A potent inhibitor of all nitric oxide synthase isoforms. Shows substantial neuroprotective effects against hypoxic damage (such as stroke) and animal models of Parkinsons disease. Crystallographic studies show that inhibition of eNOS is due to an induced cascade of conformation changes that ultimately dissociates the tetrahydrobiopterin cofactor from the enzyme.1

B686250 

A more potent inhibitor of rat cerebellar nitric oxide synthase than 7-nitroindazole.