化合物信息

Drug Groups

approved

Description

A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe and effective in aged patients and in patients with hematologic disorders. [PubChem]

Indication

For the treatment of infections due to susceptible strains of microorganisms.

Pharmacology

Ceftizoxime is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe and effective in aged patients and in patients with hematologic disorders.

Affected Organisms

Biotransformation

Ceftizoxime is not metabolized, and is excreted virtually unchanged by the kidneys in 24 hours.

Protein Binding

30% protein bound

Elimination

Ceftizoxime is not metabolized, and is excreted virtually unchanged by the kidneys in 24 hours.

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