CAS 593-56-6|O-methylhydroxylamine hydrochloride|O-Methylhydroxylamine hydrochloride|O-methylhydroxylamine hydrochloride|O-Methylhydroxylamine hydrochloride 98%|Methoxylamine hydrochloride|Methoxyam...

General Information

Structure

Molecular Formula

CH₆ClNO

Molecular Mass

83.51744

Exact Mass

83.0137915

Charge

InChI

InChI=1S/CH5NO.ClH/c1-3-2;/h2H2,1H3;1H

InChIKey

XNXVOSBNFZWHBV-UHFFFAOYSA-N

Canonic Smiles

CON.Cl

Isomeric Smiles

NOC.Cl

Calculated Properties

JChem

H Acceptors

H Donor

LogD (pH = 5.5)

-0.39036477

LogD (pH = 7.4)

-0.36289734

Log P

-0.36253566

Molar Refractivity

12.331

Polarizability

4.8056803

Polar Surface Area

35.25

Rotatable Bonds

Lipinski's Rule of Five

true

Data Source

Names and Identifiers

Synonyms

O-Methylhydroxylamine hydrochlorideMethoxylamine hydrochlorideO-Methylhydroxylamine hydrochloride 98%Methoxyamine hydrochlorideO-METHYLHYDROXYLAMINE HYDROCHLORIDEMETHOXYAMINE HYDROCHLORIDEMethoxylammonium Chloride甲氧基胺盐酸盐O-甲胲盐酸盐甲氧胺盐酸盐METHOXYAMINE(Aminooxy)methane HydrochlorideMethoxyammonium ChlorideMethoxylamine hydrochloride solutionMethoxylamine HydrochlorideO-Methoxyamine HydrochlorideHydroxylamine Methyl Ether HydrochlorideN-Methoxylamine Hydrochloride甲氧基胺盐酸盐溶液甲氧胺盐酸盐Methoxylamine hydrochloride

IUPAC Traditional name

O-methylhydroxylamine hydrochloride

IUPAC name

O-methylhydroxylamine hydrochloride

Names and Identifiers

Registration numbers

CAS Number

593-56-6

PubChem SID

248535982485350216203527124885282

Beilstein Number

EC Number

MDL Number

PubChem CID

Merck Index

Registration numbers

Properties

Related Proteins

No Data Available

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Molecular Spectra

No Data Available

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Molecule Details

MP Biomedicals

02155405

Hydrochloride

05208450

MP Biomedicals Rare Chemical collection

Sigma Aldrich

226904

Application
Reagent for the preparation of O-methyl oximes.1,2 Used to make O-methyl oximes from aldehydes3 or ketones.4
Packaging
1, 5 g in glass bottle
25 g in poly bottle
100 g in glass bottle

225517

Packaging
25, 100 g in glass bottle

67546

Other Notes
Reagent for the protection of the keto group in 1,4-diene-3-one systems1; Reagent for the derivatization of keto-groups of steroids for the detection by GLC2; Reagent for the rapid determination of neutral sugars and amino sugars in glycoproteins by GC3; Reagent used in the stereoselective reduction of ketones4

TRC

M262720

Methoxylamine is a methoxime derivative used as internal standard for Prostaglandin assays by gas chromatography-mass spectrometry.

Molecule Details

References

PubChem Literature

From Data Sources

• Herold, D.A. et al.: Prostaglandins, 33, 599 (1987)

• In the presence of KO-t-Bu and a copper catalyst in DMF, aminates nitroarenes at the ortho (predominantly) and para positions: J. Org. Chem., 61, 442 (1996).

• Reacts with aldehydes and ketones to give O-methyloximes: J. Org. Chem., 27, 914 (1962); 28, 1523 (1963); Anal. Biochem., 22, 284 (1968). Open-chain aldoses have been prepared by ozonolysis of the methoximes of fully-acylated sugars: J. Org. Chem., 54, 4957 (1989).

• As with oximes, the lithiation of methoximes results in abstraction of a proton syn to the oxygen function (coordination stabilization): J. Org. Chem., 41, 439 (1976). For a review of the alkylation of carbonyl compounds via their nitrogen-containing derivatives, see: Synthesis, 517 (1983).

References

Bioactivity

PubChem BioAssay

Bioactivity

Names and Identifiers

Synonyms

IUPAC Traditional name

O-methylhydroxylamine hydrochloride

IUPAC name

O-methylhydroxylamine hydrochloride

Registration numbers

CAS Number

593-56-6

PubChem SID

248535982485350216203527124885282

Beilstein Number

EC Number

MDL Number

PubChem CID

Merck Index

Molecule Details

Hydrochloride

MP Biomedicals Rare Chemical collection

Sigma Aldrich

226904

Application
Reagent for the preparation of O-methyl oximes.1,2 Used to make O-methyl oximes from aldehydes3 or ketones.4
Packaging
1, 5 g in glass bottle
25 g in poly bottle
100 g in glass bottle

225517

Packaging
25, 100 g in glass bottle

67546

TRC

M262720

Methoxylamine is a methoxime derivative used as internal standard for Prostaglandin assays by gas chromatography-mass spectrometry.

References

PubChem Literature

From Data Sources

• Herold, D.A. et al.: Prostaglandins, 33, 599 (1987)

• In the presence of KO-t-Bu and a copper catalyst in DMF, aminates nitroarenes at the ortho (predominantly) and para positions: J. Org. Chem., 61, 442 (1996).

Bioactivity

PubChem BioAssay

Properties

Molecule

ID:69545