Substance
ID:719586
Names and Identifiers
IUPAC Traditional name
O-methylhydroxylamine hydrochloride
IUPAC name
O-methylhydroxylamine hydrochloride
Synonyms
Methoxylamine hydrochlorideO-METHYLHYDROXYLAMINE HYDROCHLORIDE甲氧胺盐酸盐Methoxylamine hydrochloride
Registration numbers
CAS Number
Beilstein Number
MDL Number
EC Number
Merck Index
Properties
Safety Information
TSCA Listed
是
GHS Pictograms
Corrosive to metals, category 1
Skin corrosion, categories 1A,1B,1C
Serious eye damage, category 1
Hazardous to the aquatic environment
Acute hazard, category1
Chronic hazard, categories 1,2
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
GHS Precautionary statements
P260-P301+P310-P303+P361+P353-P305+P351+P338-P405-P501A
Safety Statements
26-36/37/39-45-61
RTECS
NC3980000
European Hazard Symbols
Harmful (X)
Nature polluting (N)
Corrosive (C)Storage Warning
Hygroscopic
Risk Statements
22-34-43-50
Hazard Class
8
Packing Group
III
GHS Hazard statements
H301-H317-H314-H318-H400
UN Number
UN3261
Product Information
Purity
98+%
Physical Property
Melting Point
ca 148°C dec.
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• As with oximes, the lithiation of methoximes results in abstraction of a proton syn to the oxygen function (coordination stabilization): J. Org. Chem., 41, 439 (1976). For a review of the alkylation of carbonyl compounds via their nitrogen-containing derivatives, see: Synthesis, 517 (1983).
• In the presence of KO-t-Bu and a copper catalyst in DMF, aminates nitroarenes at the ortho (predominantly) and para positions: J. Org. Chem., 61, 442 (1996).
• Reacts with aldehydes and ketones to give O-methyloximes: J. Org. Chem., 27, 914 (1962); 28, 1523 (1963); Anal. Biochem., 22, 284 (1968). Open-chain aldoses have been prepared by ozonolysis of the methoximes of fully-acylated sugars: J. Org. Chem., 54, 4957 (1989).