物质信息
ID:353122
名称和标识
IUPAC标准名
3,4-dichloro-1H-isochromen-1-one
别名
3,4-DCI3,4-Dichloroisocoumarin3,4-Dichloro-2-benzopyran-1-one
IUPAC传统名
3,4-dichloroisocoumarin
化合物性质
产品相关信息
纯度
≥99.0% (TLC)
Empirical Formula (Hill Notation)
C9H4Cl2O2
安全信息
欧盟危险性物质标志
有毒 (T)RID/ADR
UN 2811 6.1/PG 3
GHS危险声明
H301-H315-H319-H335
联合国危险货物包装类别(PG)
3
德国WGK号
3
危险公开号
25-36/37/38
联合国危险货物编号
2811
安全公开号
26-36
MSDS下载
个人保护装置
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
GHS警示性声明
P261-P301+P310-P305+P351+P338
保存温度
2-8°C
GHS警示词
Danger
联合国危险货物等级
6.1
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别1,2,3
描述信息
Other Notes
Effective concentration 5-100 μM.
Inhibitor of serine proteases1; Inhibition of porcine pancreatic elastase2
Quantity
Half-life = 20 min at pH 7.5.
Substrates
Serine protease inhibitor. Active towards a wide range of serine proteases including granzymes. Not active toward β-lactamases.
Biochem/physiol Actions
Inhibitor of serine proteases1 and porcine pancreatic elastase2. Treatment of proteasomes leads to rapid inactivation of chymotrypsin-like activity and slower inactivation of other proteases.3
Effective concentration 5-100 μM.
Inhibitor of serine proteases1; Inhibition of porcine pancreatic elastase2
Quantity
Half-life = 20 min at pH 7.5.
Substrates
Serine protease inhibitor. Active towards a wide range of serine proteases including granzymes. Not active toward β-lactamases.
Biochem/physiol Actions
Inhibitor of serine proteases1 and porcine pancreatic elastase2. Treatment of proteasomes leads to rapid inactivation of chymotrypsin-like activity and slower inactivation of other proteases.3
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