• Supplied in solution to reduce polymerization. Quantities offered relate to gross weight of solution.
• Adds to carbonyl compounds in the presence of ZnBr2: Can. J. Chem., 54, 2310 (1976).
•
The Grignard reagent, prepared by exchange with ethyl magnesium bromide, adds to carbonyl compounds to give carbinols which rearrange in acid to ɑ?-unsaturated acids. Alternatively, partial reduction of the adduct followed by hydrolysis provides a route to ɑ?-unsaturated aldehydes: J. Chem. Soc., 1823 (1949); Rec. Trav. Chim., 82, 305 (1963):
• Undergoes [2+2] cycloaddition reactions with ketenes to give cyclobutenone derivatives: J. Org. Chem., 38, 1451 (1973).
•
Rearrangement by BF3 etherate leads directly to the ethyl ester: Rec. Trav. Chim., 78, 664 (1959); Chem. Lett., 1129 (1981); 241, 1271 (1982). See also Chloroacetaldehyde diethyl acetal, L07661.• Has been used as a mild dehydrating agent in peptide synthesis: Rec. Trav. Chim., 77, 1153 (1958), and for conversion of sensitive dicarboxylic acids to their anhydrides: J. Org. Chem., 33, 3808 (1968).
有害性 (Xn)
环境危害性 (N)
易燃性 (F)