A cyclohexylamido analog of penicillanic acid. [PubChem]
Indication
For the treatment of bacterial infections caused by susceptible organisms.
Pharmacology
Cyclacillin, a penicillin, is a cyclohexylamido analog of penicillanic acid. Cyclacillin is more resistant to beta-lactamase hydrolysis than ampicillin, is much better absorbed when given by mouth and, as a result, the levels reached in the blood and in the urine are considerably higher than those obtained with the same dose of ampicillin. Cyclacillin has been replaced by newer penicillin treatments.
Toxicity
Symptoms of overdose include severe diarrhea, nausea and vomiting.
