CAS 1530-32-1|ethyltriphenylphosphanium bromide|ethyltriphenylphosphanium bromide|Ethyl(trisphenyl)phosphonium bromide|乙基三苯基溴化膦|Ethyltriphenylphosphonium bromide|TEP|Ethyltriphenylphosphoniu...

基本信息

化学结构

分子式

C₂₀H₂₀BrP

分子量

371.250561

精确质量

370.04859927

电荷

InChI

InChI=1S/C20H20P.BrH/c1-2-21(18-12-6-3-7-13-18,19-14-8-4-9-15-19)20-16-10-5-11-17-20;/h3-17H,2H2,1H3;1H/q+1;/p-1

InChIKey

JHYNXXDQQHTCHJ-UHFFFAOYSA-M

Canonic Smiles

CC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-]

Isomeric Smiles

[P+](c1ccccc1)(c1ccccc1)(c1ccccc1)CC.[Br-]

计算属性

JChem

质子受体

质子供体

LogD (pH = 5.5)

4.984599

LogD (pH = 7.4)

4.984599

Log P

4.984599

摩尔折射率

91.9698

极化性

36.28101

极化表面积

0.0

可自由旋转的化学键

里宾斯基五规则

true

数据来源

名称和标识

IUPAC传统名

ethyltriphenylphosphanium bromide

IUPAC标准名

ethyltriphenylphosphanium bromide

别名

Ethyl(trisphenyl)phosphonium bromide乙基三苯基溴化膦Ethyltriphenylphosphonium bromideTEPEthyltriphenylphosphonium BromideTriphenylethylphosphonium BromideTEP (onium compound)乙基三苯基溴化磷

名称和标识

数据登录号

PubChem SID

1620414532484565324894599

PubChem CID

EC号

Beilstein号

MDL号

CAS号

数据登录号

化合物性质

安全信息

Toxic/Harmful/Hygroscopic/Store under Argon

Hygroscopic

急性毒性（口服，皮肤接触，吸入），类别1,2,3

化合物性质

分子相关蛋白质

暂无数据

点击上传数据

分子图谱

暂无数据

点击上传数据

描述信息

Sigma Aldrich

E50604

包装
25, 100 g in poly bottle
Application
Reactant for synthesis of:
• D-amino acids from L-cysteine-derived thiazolidines1
• Leiodolide A via aldol reactions and Horner-Wadsworth-Emmons olefination2
• Cycloalkanoindolines via diastereoselective intramolecular inimo-ene reactions3
• WXYZA′ domain of maitotoxin using the coupling of key building blocks4Reactant for:
• Solid-state metathesis polycondensation to form alkyl-dipropenylthiophene monomers5
• Mizoroki-Heck cyclization and cascading Tsuji-Trost cyclization / lactonization cyclization reactions for synthesis of an ABC ring system6

04997

Application
Reactant for synthesis of:
• D-amino acids from L-cysteine-derived thiazolidines1
• Leiodolide A via aldol reactions and Horner-Wadsworth-Emmons olefination2
• Cycloalkanoindolines via diastereoselective intramolecular inimo-ene reactions3
• WXYZA′ domain of maitotoxin using the coupling of key building blocks4Reactant for:
• Solid-state metathesis polycondensation to form alkyl-dipropenylthiophene monomers5
• Mizoroki-Heck cyclization and cascading Tsuji-Trost cyclization / lactonization cyclization reactions for synthesis of an ABC ring system6

TRC

E931950

Ethyltriphenylphosphonium Bromide is used as a wittig reagent. Ethyltriphenylphosphonium Bromide and other phosphonium salts show antiviral activity.

描述信息

参考文献

PubChem文献

数据源提供

• Romanov, G.V. et al.: Khim.-Farm. Zhur., 24, 28 (1990)

• Reaction of the phosphorane (generated using 1 mole of n-BuLi) with an aldehyde at low temperature, followed by a second mole of n-BuLi, gives the -oxido phosphonium ylide which can then be reacted with 1,2-diiodoethane to give (Z)-2-iodo-2-alkenes with high stereoselectivity: J. Chem. Soc., Perkin 1, 1331 (1995). See Appendix 1.

参考文献

生物活性

PubChem BioAssay

生物活性