化合物信息

S2605  

Biological Activity:
Idebenone is a synthetic analog of coenzyme Q10 (CoQ10) and a brain stimulant. Idebenone is used for the treatment of Alzheimer’s disease and other cognitive defects. Idebenone is inhibits lipoperoxide formation.is a synthetic analog of coenzyme Q10 (CoQ10). Idebenone increases brain energy levels and rejuvinates cell mitochondria throughout the whole body. Most recently, idebenone has been shown to be very supportive in the treatment of Friedreich’s ataxia and Duchenne muscular dystrophy. Chemically, idebenone is an organic compound of the quinone family. Idebenone has properties similar to CoQ10 in its antioxidant properties, and has therefore been used in anti-aging on the basis of free-radical theory. [1][2][3]References on Idebenone[1] Nippon Yakurigaku Zasshi. , 1988 May, 91(5):295-9[2] http://en.wikipedia.org/wiki/Idebenone, , [3] Lancet Neurol., 2007 Oct, 6(10):878-86

I170050 

Ubiquinone derivative with protective effects against cerebral ischemia. Nootropic.

CHEBI:31687 

A member of the class of 1,4-benzoquinones which is substituted by methoxy groups at positions 2 and 3, by a methyl group at positions 5, and by a 10-hydroxydecyl group at positions 6. Initially developed for the treatment of Alzheimer's disease, benefits were modest; it was subsequently found to be of benefit for the symptomatic treatment of Friedreich's ataxia.