化合物信息

80328 

Biochem/physiol Actions
Spectrum of Activity: Gram positive cocci and taxoplasma. Especially active against anaerobic bacteria.Mode of Action: Inhibits protein synthesis in bacterial by binding the 50s ribosomal subunit.
Other Notes
Antibacterial and antiprotozoal antibiotic of the licosamide class.

C6427 

Biochem/physiol Actions
Spectrum of Activity: Gram positive cocci and taxoplasma. Especially active against anaerobic bacteria.Mode of Action: Inhibits protein synthesis in bacterial by binding the 50s ribosomal subunit.
Clindamycin 2-phosphate is a pharmacological tyrosyl-DNA phosphodiesterase (Tdp1) inhibitor. Clindamycin 2-phosphate can repair DNA topoisomerase I-DNA covalent complexes by hydrolyzing the tyrosyl-DNA bond. It inhibits protein synthesis in bacteria by binding the 50s ribosomal subunit. 2. Spectrum of Activity: Gram positive cocci and taxoplasma. Especially active against anaerobic bacteria.
Other Notes
Antibacterial and antiprotozoal antibiotic of the licosamide class.
Application
Clindamycin 2-phosphate is an aminoglycoside antibiotic that has been used to study the cytoxicity of antibiotics on human cell lines 1, Bacterial protein synthesis and peptide translation, and the inhibition of human Tyrosyl-DNA Phosphodiesterase 2.