• Reactant for regioselective synthesis of oxopyrrolidine analogs via iodine-catalyzed Markovnikov addition1 • Reactant for preparation of indoles by Bartoli reductive cyclization as useful intermediates in medicinal chemistry research2 • Reactant for synthesis of carbon-11-labeled 4-aryl-4H-chromenes as new PET agents for imaging of apoptosis in cancer3 • Reactant for preparation of HCV inhibitors4 • Reactant for preparation of indol-3-yl tetramethylcyclopropyl ketones as CB2 cannabinoid receptor ligands5 • Reactant for preparation of 4-aryl-4H-chromenes as apoptosis inducers6
Indole derivative as substrate-binding; N297Q and I300V mutants of cytochrome P 450 2A6 display expansion of substrate specificity of cytochrome P 450 2A6 to oxidize substituted indoles.