物质信息
ID:347140
名称和标识
IUPAC标准名
2-bromo-2-chloro-1,1,1-trifluoroethane
IUPAC传统名
halothane
别名
Halothane2-Bromo-2-chloro-1,1,1-trifluoroethane
化合物性质
安全信息
个人保护装置
Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US)
安全公开号
53-23-26-36/37-45
GHS危险品标识
呼吸道过敏，类别1
生殖细胞突变，类别1A，1B，2
致癌性，类别1A，1B，2
生殖毒性，类别1A，1B，2
特定目标器官毒性 – 一次接触，类别1,2
特定目标器官毒性 – 反复接触，类别1,2
吸入危险，类别1
腐蚀金属，类别1
腐蚀皮肤，类别1A，1B，1C
严重眼损伤，类别1
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
GHS警示词
Danger
GHS警示性声明
P201-P261-P280-P305+P351+P338-P308+P313
MSDS下载
危险公开号
61-37/38-41
RTECS编号
KH6550000
德国WGK号
3
GHS危险声明
H315-H318-H335-H360
欧盟危险性物质标志
有毒 (T)产品相关信息
纯度
≥99%
线性分子式
BrCH(Cl)CF3
其他组分
0.01% thymol as stabilizer
药理学性质
相关基因信息
human ... ATP5D(513), GLRA1(2741), GRIA1(2890), KCNN4(3783)
理化性质
沸点
50.2 °C(lit.)
密度
1.872 g/mL at 25 °C(lit.)
折射率
n20/D 1.369(lit.)
蒸汽压
4.5 psi ( 20 °C)
描述信息
包装
125, 250 mL in glass bottle
Application
2-Bromo-2-chloro-1,1,1-trifluoroethane, or halothane, has been used in a study that combined molecular simulations with free energy simulations to study solvation of halothane in polarizable water and methanol. Halothane has also been used in a study to investigate the interaction of anesthetics with the Rho GTPase regulator Rho GDP dissociation inhibitor.
Biochem/physiol Actions
Inhalation anesthetic. In an effect believed to be independent of anesthesia, halothane inhibits synthesis of 5-hydroxytryptamine in brain tissue, probably at the tryptophan hydroxylase step.1
125, 250 mL in glass bottle
Application
2-Bromo-2-chloro-1,1,1-trifluoroethane, or halothane, has been used in a study that combined molecular simulations with free energy simulations to study solvation of halothane in polarizable water and methanol. Halothane has also been used in a study to investigate the interaction of anesthetics with the Rho GTPase regulator Rho GDP dissociation inhibitor.
Biochem/physiol Actions
Inhalation anesthetic. In an effect believed to be independent of anesthesia, halothane inhibits synthesis of 5-hydroxytryptamine in brain tissue, probably at the tryptophan hydroxylase step.1
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