化合物信息

Drug Groups

approved

Description

One of the histamine H1 antagonists with little sedative action. It is used in treatment of hay fever, rhinitis, allergic dermatoses, and pruritus. [PubChem]

Indication

Pheniramine is an antihistamine used to treat allergic conditions such as hay fever or urticaria.

Pharmacology

Pheniramine is an antihistamine used to treat allergic conditions such as hay fever or urticaria. It is generally sold in combination with other medications, rather than as a stand-alone drug. Allergies are caused by an excessive type 1 hypersensitivity response of the body to allergens, mediated by inappropriate histamine signalling. By inhibiting the binding of histamine, antihistamines decrease the normal histamine response from cells, consequently decreasing allergic symptoms.

Affected Organisms

Biotransformation

Hepatic hydroxylation, demethylation and glucuronidation.

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