Biochem/physiol Actions β-Lapachone is a naturally occurring quinone obtained from the bark of the lapacho tree (Tabebuia avellanedae) with cancer chemopreventive properties. Induces apoptosis in HL-60 and human prostate cancer cells.1
β-Lapachone is a naturally occurring quinone obtained from the bark of the lapacho tree (Tabebuia avellanedae) with cancer chemopreventive properties. Induces apoptosis in HL-60 and human prostate cancer cells.
A benzochromenone that is 3,4-dihydro-2H-benzo[h]chromene-5,6-dione substituted by geminal methyl groups at position 2. Isolated from Tabebuia avellanedae, it exhibits antineoplastic and anti-inflammatory activities.
参考文献
PubChem文献
数据源提供
• Stuart, K., et al.: J. Clin. Invest., 118, 1301 (2006)
• Renslo, A., et al.: Nat. Chem. Biol., 2, 701 (2006)
• Martin, R., et al.: Science, 25, 1680 (2006)
• Hopkins, A., et al.: Nat. Chem. Biol., 4, 682 (2006)