CAS 996-50-9|N-TRIMETHYLSILYLDIETHYLAMINE|N,N-Diethyl-1,1,1-trimethylsilylamine|diethyl(trimethylsilyl)amine|diethyl(trimethylsilyl)amine|N-TRIMETHYLSILYL DIETHYLAMINE|N,N-Diethyltrimethylsilylamine...

基本信息

化学结构

分子式

C₇H₁₉NSi

分子量

145.31796

精确质量

145.12867615

电荷

InChI

InChI=1S/C7H19NSi/c1-6-8(7-2)9(3,4)5/h6-7H2,1-5H3

InChIKey

JOOMLFKONHCLCJ-UHFFFAOYSA-N

Canonic Smiles

CCN([Si](C)(C)C)CC

Isomeric Smiles

CCN(CC)[Si](C)(C)C

计算属性

JChem

质子受体

质子供体

LogD (pH = 5.5)

-1.4219337

LogD (pH = 7.4)

-1.3960248

Log P

1.8515

摩尔折射率

40.7309

极化性

18.099138

极化表面积

3.24

可自由旋转的化学键

里宾斯基五规则

true

数据来源

名称和标识

别名

N-TRIMETHYLSILYLDIETHYLAMINEN,N-Diethyl-1,1,1-trimethylsilylamineN-TRIMETHYLSILYL DIETHYLAMINE(二乙氨基)三甲基硅烷N,N-DiethyltrimethylsilylamineN-(三甲基甲硅烷基)二乙胺N,N-二乙基三甲基甲硅烷胺TMSDEAN-(Trimethylsilyl)diethylamine(Diethylamino)trimethylsilaneN-(三甲基硅基)二乙胺N-(Trimethylsilyl)diethylamine

IUPAC传统名

diethyl(trimethylsilyl)amine

IUPAC标准名

diethyl(trimethylsilyl)amine

名称和标识

数据登录号

CAS号

EC号

MDL号

Beilstein号

PubChem SID

248477722486462616209198724859530

PubChem CID

70454

数据登录号

化合物性质

分子相关蛋白质

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分子图谱

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描述信息

MP Biomedicals

02157087

(N,N-Diethyl-1,1,1-trimethylsilylamine)
Purity: 95%
1 ml = approx. 0.77 g

05223114

MP Biomedicals Rare Chemical collection

Sigma Aldrich

127256

包装
25, 100 g in glass bottle

394890

包装
5 mL in glass bottle

32575

Other Notes
硅烷化试剂1,2

32574

General description
请访问我们的传感器应用页面以了解更多信息。
法律信息
Selectophore 商标 Sigma-Aldrich GmbH

描述信息

参考文献

PubChem文献

数据源提供

• In the presence of MeI, primary amines such as aniline are converted to their N,N-bis(trimethylsilyl) derivatives: J. Organomet. Chem., 510, 1 (1996), and ketones to silyl enol ethers in high yield: Organometallics, 16, 2204 (1997). The combination with an alkyl iodide or bromide also provides a convenient method for generating the iodo- or bromotrialkylsilane equivalent in ring-opening of cyclic ethers. With 1 mol of reagent the main product is the ω-siloxy alkyl halide; excess reagent affords the terminal dihalide: J. Org. Chem., 64, 8024 (1999).

• Moderately powerful silylating agent which functions as its own base (see Appendix 4). In the silylation of alcohols, the reagent is sensitive to steric effects. Thus, the equatorial hydroxyl group of 3-?-tropanol can be silylated selectively: Acta Chim. Acad. Sci. Hung., 58, 189 (1968); J. Am. Chem. Soc., 96, 5876 (1974).

• Promotes direct 1,4-addition of ɑ-unsubstituted aldehydes to electron deficient olefins, specifically with enones to give δ-keto aldehydes: J. Chem. Soc., Perkin 1, 316 (2001). Alternative conditions were found to be ineffective.

参考文献

生物活性

PubChem BioAssay

生物活性