CAS 16940-66-2|SODIUM BOROHYDRIDE|sodium boranuide|potassium borohydride|Sodium Tetrahydroborate|Sodium boranuide|sodium boranuide|Sodium tetrahydridoborate|Sodium borohydride|四氢硼酸钠|硼氢化钠|Ve...

基本信息

化学结构

分子式

BNa

分子量

33.80077

精确质量

33.99907468

电荷

InChI

InChI=1S/BH4.Na/h1H4;/q-1;+1

InChIKey

YOQDYZUWIQVZSF-UHFFFAOYSA-N

Canonic Smiles

[BH3-].[Na+]

Isomeric Smiles

[BH3-].[Na+]

计算属性

JChem

质子受体

质子供体

LogD (pH = 5.5)

-1.804

LogD (pH = 7.4)

-1.804

Log P

-1.804

摩尔折射率

3.2

极化性

3.2773068

极化表面积

0.0

可自由旋转的化学键

里宾斯基五规则

true

数据来源

名称和标识

别名

SODIUM BOROHYDRIDESodium TetrahydroborateSodium tetrahydridoborateSodium borohydride四氢硼酸钠硼氢化钠VenPure® AF硼氢化钠溶液Sodium borohydrideCobalt-doped sodium borohydride钴掺杂的硼氢化钠氧化铝负载硼氢化钠Sodium borohydride solutionVenPure® SF硼氢化钠VenPure®Sodium borohydride on aluminum oxideSodium borohydride, stable aq. soln., 4.4M in 14M NaOH硼氢化钠, 稳定水溶液, 4.4M的氢氧化钠溶液(14M)

IUPAC标准名

sodium boranuide

IUPAC传统名

potassium borohydride sodium boranuide

IUPAC系统名

Sodium boranuide

名称和标识

数据登录号

化合物性质

分子相关蛋白质

暂无数据

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分子图谱

暂无数据

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描述信息

MP Biomedicals

02102894

Hygroscopic
Purity: 98-99%
Crystalline
Excellent reducing agent.

Wikipedia

Sodium_borohydride

Sigma Aldrich

452165

Features and Benefits
配制用于去除颜色和气味
包装
100 g in poly bottle
2 kg in steel drum
Legal Information
Rohm & Haas 产品
法律信息
VenPure 注册商标 Rohm and Haas Chemicals LLC

686018

Analysis Note
可按要求提供氢含量、XRD 谱图和金属纯度数据。
General description
Atomic number of base material: 11
包装
10 g in poly bottle
Protocols & Applications
Metal Borohydrides as Hydrogen Storage Materials
Boron-based Hydrogen Storage

632287

包装
100, 500 g in poly bottle
2 kg in steel drum
Legal Information
Rohm & Haas 产品
法律信息
VenPure 注册商标 Rohm and Haas Chemicals LLC

556351

包装
25 mL in glass bottle

247677

Features and Benefits
便利的氢气固体源。每片与水接触可以释放 ~500mL 氢气。用于在生物实验中制造厌氧的还原性气氛。掺钴
包装
50 g in poly bottle

215511

包装
100 mL in Sure/Seal™

200972

包装
100 mL in Sure/Seal™

452882

包装
2 kg in steel drum
5, 25, 100, 500 g in poly bottle
Legal Information
Rohm & Haas 产品
法律信息
VenPure 注册商标 Rohm and Haas Chemicals LLC
Application
已通过配体诱导并采用硼氢化钠还原的 AuCl3 制备了胶体金溶液中的纳米晶超晶格。1来自硼氢化钠的氢负离子的亲核加成反应是一种低廉的替代方法，用于 Baylis-Hillman 反应形成 [E]-α-甲基肉桂酸。2

452904

包装
1 L in poly bottle
25 mL in poly bottle
Legal Information
Rohm & Haas 产品

452890

包装
2 kg in steel drum
25, 100, 500 g in poly bottle
Legal Information
Rohm & Haas 产品
法律信息
VenPure 注册商标 Rohm and Haas Chemicals LLC

452874

包装
100 g in poly bottle
25 g in amber poly
2 kg in steel drum
500 g in amber poly
Legal Information
Rohm & Haas 产品
法律信息
VenPure 注册商标 Rohm and Haas Chemicals LLC
Application
已通过配体诱导并采用硼氢化钠还原的 AuCl3 制备了胶体金溶液中的纳米晶超晶格。1来自硼氢化钠的氢负离子的亲核加成反应是一种低廉的替代方法，用于 Baylis-Hillman 反应形成 [E]-α-甲基肉桂酸。2

213462

包装
25, 100 g in poly bottle
Application
已通过配体诱导并采用硼氢化钠还原的 AuCl3 制备了胶体金溶液中的纳米晶超晶格。1来自硼氢化钠的氢负离子的亲核加成反应是一种低廉的替代方法，用于 Baylis-Hillman 反应形成 [E]-α-甲基肉桂酸。2
法律信息
ReagentPlus 注册商标 Sigma-Aldrich Co. LLC

243620

Application
比游离 NaBH4 更具选择性、更易于使用的负载试剂。
包装
10, 50 g in glass bottle

480886

包装
25, 100 g in poly bottle
Application
已通过配体诱导并采用硼氢化钠还原的 AuCl3 制备了胶体金溶液中的纳米晶超晶格。1来自硼氢化钠的氢负离子的亲核加成反应是一种低廉的替代方法，用于 Baylis-Hillman 反应形成 [E]-α-甲基肉桂酸。2

452173

Features and Benefits
配制用于去除颜色和气味
包装
100, 500 g in poly bottle
Legal Information
Rohm & Haas 产品
法律信息
VenPure 注册商标 Rohm and Haas Chemicals LLC

71320

Other Notes
羧酸衍生物的还原1,2

描述信息

参考文献

PubChem文献

数据源提供

• Hydroboration of olefins has also been reported under similar conditions: Synlett, 997 (2000).

• The combination of borohydride and iodine (in situ borane) reduces acids to alcohols: J. Org. Chem., 56, 5964 (1991); amino acids to amino alcohols: J. Org. Chem., 58, 3568 (1993); and effects reduction of esters, amides and nitriles, as well as hydroboration of alkenes: Tetrahedron, 45, 4623 (1992). See also Boron trifluoride diethyl etherate, A15275, and Sodium triacetoxyborohydride, B22060.

• The reduction of aldehydes and ketones to alcohols occurs in alcoholic or aqueous media. For highly selective reduction of aldehydes in the presence of ketones, see: Synth. Commun., 18, 1927 (1988). For enantioselective reduction, see L-tert-Leucine, L13707. Borohydride reductions can be carried out in organic solvents, e.g. toluene, under phase-transfer conditions, amenable to scale-up: Org. Process Res. Dev., 1, 287 (1997).

• LiCl: reduction of amino acids via Me esters: Tetrahedron Lett., 39, 917 (1998). CaCl₂: selective 1,2-reduction enones: Chem. Lett., 1847 (1991). CeCl₃: increased selectivity for 1,2-reduction of enones: J. Chem. Soc., Chem. Commun., 601 (1978); reduction of ketones in the presence of aldehydes: J. Am. Chem. Soc., 101, 5848 (1979). CuCl: dehalogenation of aryl iodides and bromides: J. Org. Chem., 54, 5308 (1989); reduction of nitro compounds: Chem. Ind. (London), 75 (1984). CuSO₄: reduction of esters, alkenes, nitriles and nitro compounds; amides and acids inert: Synlett, 419 (1990) [but see also Synlett, 79 (1993): Cu(OAc)₂ preferred for reduction of nitro-groups]; reduction of azides: Synth. Commun., 24, 549 (1994). NiCl₂: generation in situ of nickel boride, as an alternative to Raney nickel for desulfurizations: Synth. Commun., 16, 779 (1986); J. Chem. Soc., Chem. Commun., 819 (1990); J. Org. Chem., 57, 1986 (1992); 58, 2407 (1993); phenols and enols have also been deoxygenated: J. Chem. Soc., Perkin 1, 1897 (1992), and aryl nitrile reduced to benzylamines: Synth. Commun, 32, 1265 (2002). For conversion to Zn(BH₄)₂, see Zinc chloride, A16281. InCl₃: radical reducing system - alternative to Bu₃SnH: J. Am. Chem. Soc., 124, 906 (2002)_.

• A vast number of modified borohydride reagents have been reported, with the objective either of increasing the reducing power or improving selectivity. Many examples involve combinations with metal salts:

• Reductive alkylation of amines can be effected with NaBH₄/formaldehyde; see e.g.: Synthesis, 743 (1980); or TFA: Synthesis, 709 (1987). See also Sodium cyanoborohydride, 87839. Reductive alkylation of aromatic amines with a variety of aldehydes and ketones has been reported, using NaBH₄/H₂SO₄: Synthesis, 121 (1993).

• Acid chlorides are readily reduced to alcohols; controlled reduction at -78^o to give the aldehyde has been reported; see, e.g.: Synth. Commun., 12, 839 (1982). See also Bis(triphenylphosphine)copper(I) borohydride, A13730. For an indirect method of reduction, see Triethyl phosphite, L00339.

• Monograph: J. Seyden-Penne, Reductions by the Alumino- and Borohydrides In Organic Synthesis, 2nd ed., Wiley, N.Y. (1997).

• For a brief feature on uses of the reagent in synthesis, see: Synlett, 182 (2005).

参考文献

生物活性

PubChem BioAssay

生物活性

名称和标识

别名

IUPAC标准名

sodium boranuide

IUPAC传统名

potassium borohydride sodium boranuide

IUPAC系统名

Sodium boranuide

描述信息

MP Biomedicals

02102894

Hygroscopic
Purity: 98-99%
Crystalline
Excellent reducing agent.

Wikipedia

Sodium_borohydride

Sigma Aldrich

452165

Features and Benefits
配制用于去除颜色和气味
包装
100 g in poly bottle
2 kg in steel drum
Legal Information
Rohm & Haas 产品
法律信息
VenPure 注册商标 Rohm and Haas Chemicals LLC

686018

632287

包装
100, 500 g in poly bottle
2 kg in steel drum
Legal Information
Rohm & Haas 产品
法律信息
VenPure 注册商标 Rohm and Haas Chemicals LLC

556351

包装
25 mL in glass bottle

247677

Features and Benefits
便利的氢气固体源。每片与水接触可以释放 ~500mL 氢气。用于在生物实验中制造厌氧的还原性气氛。掺钴
包装
50 g in poly bottle

215511

包装
100 mL in Sure/Seal™

200972

包装
100 mL in Sure/Seal™

452882

452904

包装
1 L in poly bottle
25 mL in poly bottle
Legal Information
Rohm & Haas 产品

452890

包装
2 kg in steel drum
25, 100, 500 g in poly bottle
Legal Information
Rohm & Haas 产品
法律信息
VenPure 注册商标 Rohm and Haas Chemicals LLC

452874

213462

243620

Application
比游离 NaBH4 更具选择性、更易于使用的负载试剂。
包装
10, 50 g in glass bottle

480886

452173

Features and Benefits
配制用于去除颜色和气味
包装
100, 500 g in poly bottle
Legal Information
Rohm & Haas 产品
法律信息
VenPure 注册商标 Rohm and Haas Chemicals LLC

71320

Other Notes
羧酸衍生物的还原1,2

参考文献

PubChem文献

数据源提供

• Hydroboration of olefins has also been reported under similar conditions: Synlett, 997 (2000).

• Monograph: J. Seyden-Penne, Reductions by the Alumino- and Borohydrides In Organic Synthesis, 2nd ed., Wiley, N.Y. (1997).

• For a brief feature on uses of the reagent in synthesis, see: Synlett, 182 (2005).

生物活性

PubChem BioAssay

化合物性质

化合物信息

ID:102741