Substance
ID:73931
Names and Identifiers
IUPAC name
benzyl 2-{2-[(acetylsulfanyl)methyl]-3-phenylpropanamido}acetate
IUPAC Traditional name
benzyl 2-{2-[(acetylsulfanyl)methyl]-3-phenylpropanamido}acetate
Synonyms
AcetorphanRacecadotril
Registration numbers
CAS Number
Properties
Product Information
Salt Data
Free Base
Safety Information
Storage Condition
-20°C
Molecule Details
Research Area: Metabolic Disease
Biological Activity:
Racecadotril is a peripherally acting enkephalinase inhibitor with an IC50 of 4.5 µM.Unlike other medications used to treat diarrhea, which reduce intestinal motility, racecadotril has an antisecretory effect—it reduces the secretion of water and electrolytes into the intestine. A small randomized controlled trial found racecadotril to significantly reduce the duration and volume of watery diarrhea in children when given as an adjunct to oral rehydration therapy. [1][2]References on Racecadotril (Acetorphan)[1] Int J Antimicrob Agents., 2000 Feb, 14(1):75-9.[2] http://en.wikipedia.org/wiki/Racecadotril, ,
Biological Activity:
Racecadotril is a peripherally acting enkephalinase inhibitor with an IC50 of 4.5 µM.Unlike other medications used to treat diarrhea, which reduce intestinal motility, racecadotril has an antisecretory effect—it reduces the secretion of water and electrolytes into the intestine. A small randomized controlled trial found racecadotril to significantly reduce the duration and volume of watery diarrhea in children when given as an adjunct to oral rehydration therapy. [1][2]References on Racecadotril (Acetorphan)[1] Int J Antimicrob Agents., 2000 Feb, 14(1):75-9.[2] http://en.wikipedia.org/wiki/Racecadotril, ,
Molecular Spectra
No Data Available
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References
• Schwartz JC et al. Int J Antimicrob Agents. 2000