Molecule

S2503 

Research Area: Metabolic Disease
Biological Activity:
Racecadotril is a peripherally acting enkephalinase inhibitor with an IC50 of 4.5 µM.Unlike other medications used to treat diarrhea, which reduce intestinal motility, racecadotril has an antisecretory effect—it reduces the secretion of water and electrolytes into the intestine. A small randomized controlled trial found racecadotril to significantly reduce the duration and volume of watery diarrhea in children when given as an adjunct to oral rehydration therapy. [1][2]References on Racecadotril (Acetorphan)[1] Int J Antimicrob Agents., 2000 Feb, 14(1):75-9.[2] http://en.wikipedia.org/wiki/Racecadotril, ,

SML0043 

Biochem/physiol Actions
Racecadotril is a neutral endopeptidase inhibitor, an antidiarrheal drug which acts as a peripherally acting enkephalinase inhibitor.

R070600 

Antidiarrheal; enkephalinase inhibitor, reducing the amount of water and electrolytes into the intestine.