Substance
ID:714669
Names and Identifiers
IUPAC Traditional name
2,4,6-collidine
IUPAC name
2,4,6-trimethylpyridine
Synonyms
2,4,6-三甲基吡啶2,4,6-Trimethylpyridine2,4,6-Collidine
Registration numbers
MDL Number
Beilstein Number
CAS Number
EC Number
Merck Index
Properties
Physical Property
Flash Point
54°C(129°F)
Boiling Point
171-172°C
Refractive Index
1.4980
Melting Point
-43°C
Density
0.916
Product Information
Purity
99%
Safety Information
European Hazard Symbols
Harmful (X)Safety Statements
26-36/37
UN Number
UN1992
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Flammable gases, category 1
Flammable aerosols, categories 1,2
Flammable liquids, categories 1,2,3
Self-reactive substances and mixtures, Types B,C,D,E,F
Pyrophoric liquids, category 1
Pyrophoric solids, category 1
Self-heating substances and mixtures
Substances and mixtures, which in contact with water, emit flammable gases, categories 1,2,3
Organic peroxides, Types B,C,D,E,F
Hazard Class
3
GHS Precautionary statements
P210-P241-P303+P361+P353-P305+P351+P338-P405-P501A
TSCA Listed
是
Risk Statements
10-21/22-36/37/38
Packing Group
III
GHS Hazard statements
H226-H302-H312-H315-H319-H335
RTECS
UU0970000
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Superior base for peptide coupling reactions, causing less racemization than the more commonly used N-ethyldiisopropylamine or N-methylmorpholine: J. Org. Chem., 59,695 (1994). For comparison with other hindered bases, see: J. Org. Chem., 61, 2460 (1996). For peptide reagents, see Appendix 6.
• Solvent for various O-alkyl cleavage reaction by LiI, including hindered esters: J. Org. Chem., 28, 2184 (1963), and methyl ethers of phenols: Chem. Commun., 616 (1969).
• Hindered base. For use in the dehydrochlorination of ɑ-chloroketones to enones, see: Org. Synth. Coll., 4, 162 (1963). For use in combination with Trifluoromethanesulfonic anhydride, A11767 for the generation of ketenimines from olefins, see N,N-Dimethylacetamide, A10924.