CAS 108-75-8|2,4,6-trimethylpyridine|2,4,6-Collidine|2,4,6-Trimethylpyridine|2,4,6-collidine|可力丁|2,4,6-三甲基吡啶|sym-Collidine|2,4,6-Trimethylpyridine|2,4,6-三甲基氮杂苯|2,4,6-Trimethylpyridine|...

General Information

Structure

Molecular Formula

C₈H₁₁N

Molecular Mass

121.17964

Exact Mass

121.08914936

Charge

InChI

InChI=1S/C8H11N/c1-6-4-7(2)9-8(3)5-6/h4-5H,1-3H3

InChIKey

BWZVCCNYKMEVEX-UHFFFAOYSA-N

Canonic Smiles

Cc1cc(C)nc(c1)C

Isomeric Smiles

n1c(cc(cc1C)C)C

Calculated Properties

JChem

H Acceptors

H Donor

LogD (pH = 5.5)

-0.0325026

LogD (pH = 7.4)

1.2789286

Log P

1.5317351

Molar Refractivity

38.1253

Polarizability

14.741129

Polar Surface Area

12.89

Rotatable Bonds

Lipinski's Rule of Five

true

Data Source

Names and Identifiers

IUPAC name

2,4,6-trimethylpyridine

Synonyms

2,4,6-Collidine2,4,6-Trimethylpyridine可力丁2,4,6-三甲基吡啶sym-Collidine2,4,6-Trimethylpyridine2,4,6-三甲基氮杂苯2,4,6-Trimethylpyridine2,4,6-COLLIDINE2,4,6-Collidine

IUPAC Traditional name

2,4,6-collidine

Names and Identifiers

Registration numbers

Beilstein Number

CAS Number

MDL Number

EC Number

PubChem SID

2484852324856725162076155

PubChem CID

7953

Merck Index

149718

Registration numbers

Properties

Related Proteins

No Data Available

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Molecular Spectra

No Data Available

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Molecule Details

MP Biomedicals

02150707

Refractionated
Reagent for DNA synthesis
1 ml = approx. 0.91 g

02190173

Note: For use in tissue fixation for electron microscopy
1 ml=approx. 0.91 g

Sigma Aldrich

27692

Application
Tissue fixative for electron microscopy.

142387

Application
Tissue fixative for electron microscopy.
Useful solvent for the cleavage of hindered esters by anhydrous lithium iodide.
General description
Hindered base.
Packaging
1 L in glass bottle
5, 100, 500 mL in glass bottle
Legal Information
ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

27690

Application
Tissue fixative for electron microscopy.

Molecule Details

References

PubChem Literature

From Data Sources

• Bennett, H.S. and Luft, J.H., J. Biophys. Biochem. Cytol. , 6 : 113 (1959).

• Superior base for peptide coupling reactions, causing less racemization than the more commonly used N-ethyldiisopropylamine or N-methylmorpholine: J. Org. Chem., 59,695 (1994). For comparison with other hindered bases, see: J. Org. Chem., 61, 2460 (1996). For peptide reagents, see Appendix 6.

• Hindered base. For use in the dehydrochlorination of ɑ-chloroketones to enones, see: Org. Synth. Coll., 4, 162 (1963). For use in combination with Trifluoromethanesulfonic anhydride, A11767 for the generation of ketenimines from olefins, see N,N-Dimethylacetamide, A10924.

• Solvent for various O-alkyl cleavage reaction by LiI, including hindered esters: J. Org. Chem., 28, 2184 (1963), and methyl ethers of phenols: Chem. Commun., 616 (1969).

References

Bioactivity

PubChem BioAssay

Bioactivity

Names and Identifiers

IUPAC name

2,4,6-trimethylpyridine

Synonyms

2,4,6-Collidine2,4,6-Trimethylpyridine可力丁2,4,6-三甲基吡啶sym-Collidine2,4,6-Trimethylpyridine2,4,6-三甲基氮杂苯2,4,6-Trimethylpyridine2,4,6-COLLIDINE2,4,6-Collidine

IUPAC Traditional name

2,4,6-collidine

Registration numbers

Beilstein Number

CAS Number

MDL Number

EC Number

PubChem SID

2484852324856725162076155

PubChem CID

Merck Index

Molecule Details

Refractionated
Reagent for DNA synthesis
1 ml = approx. 0.91 g

02190173

Note: For use in tissue fixation for electron microscopy
1 ml=approx. 0.91 g

Sigma Aldrich

27692

Application
Tissue fixative for electron microscopy.

142387

27690

Application
Tissue fixative for electron microscopy.

References

PubChem Literature

From Data Sources

• Bennett, H.S. and Luft, J.H., J. Biophys. Biochem. Cytol. , 6 : 113 (1959).

• Solvent for various O-alkyl cleavage reaction by LiI, including hindered esters: J. Org. Chem., 28, 2184 (1963), and methyl ethers of phenols: Chem. Commun., 616 (1969).

Bioactivity

PubChem BioAssay

Properties

Molecule

ID:89274