Substance

ID:6577

Names and Identifiers
Brand Name
AndantonActaprontOdantolNilergexUdantol
IUPAC name
dimethyl(1-{9-thia-2,4-diazatricyclo[8.4.0.0^{3,8}]tetradeca-1(10),3,5,7,11,13-hexaen-2-yl}propan-2-yl)amine
Synonyms
IsothipendylIsothipendylum
IUPAC Traditional name
isothipendyl
Registration numbers
CAS Number
Properties
No Data Available
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Molecule Details
Drug Groups
approved
Description
Isothipendyl is an antihistamine and anticholinergic used as an antipruritic.
Indication
For the topical treatment of itching associated with allergic reactions.
Pharmacology
Isothipendyl, an azaphenothiazine derivative, competitively binds to histamine (H1) receptors, resulting in inhibition of the pharmacological effects of histamines. It also has some sedative, anticholinergic and antiserotoninergic effects.
Affected Organisms
Humans and other mammals
References
• Moreau A, Dompmartin A, Dubreuil A, Leroy D: Phototoxic and photoprotective effects of topical isothipendyl. Photodermatol Photoimmunol Photomed. 1995 Apr;11(2):50-4. [Pubmed]
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Molecular Spectra
No Data Available
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References
• Moreau A, Dompmartin A, Dubreuil A, Leroy D: Phototoxic and photoprotective effects of topical isothipendyl. Photodermatol Photoimmunol Photomed. 1995 Apr;11(2):50-4. Pubmed