Substance
ID:389856
Names and Identifiers
IUPAC Traditional name
(2E)-3-{4-[(1E)-3-(3-fluorophenyl)-3-oxoprop-1-en-1-yl]-1-methylpyrrol-2-yl}-N-hydroxyprop-2-enamide
IUPAC name
(2E)-3-{4-[(1E)-3-(3-fluorophenyl)-3-oxoprop-1-en-1-yl]-1-methyl-1H-pyrrol-2-yl}-N-hydroxyprop-2-enamide
Synonyms
3-[4-(3-(3-Fluorophenyl)-3-oxo-1-propen-1-yl)-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-2-propenamideMC 1568
Registration numbers
CAS Number
Properties
Product Information
Certificate of Analysis
Safety Information
MSDS Link
Molecule Details
A selective class II (IIa) histone deacetylase (HDAC II) inhibitor. It exhibits tissue-selective inhibition between members of class II acetylases in vivo, particularly in skeletal muscle and the heart. It arrests myogenesis through the stabilization of m
Molecular Spectra
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References
• Mai, A. et al.: J.Med.Chem., 48, 3344 (2007)
• Mai, A. et al.: Mol.Pharmacol., 72, 1111 (2007)
• Nebbioso, A. et al.: Eur. Mol. Biol. Org. Rep., 10, 776 (2007)