Substance
ID:369020
Names and Identifiers
IUPAC name
2-amino-2-(hydroxymethyl)propane-1,3-diol
IUPAC Traditional name
tris buffer
Synonyms
2-Amino-2-(hydroxymethyl)-1,3-propanediolTrometamolTHAMTris base2-氨基-2-(羟甲基)-1,3-丙二醇Tris 碱氨基丁三醇三羟甲基氨基甲烷Trizma® baseTrizma® 碱Tris(hydroxymethyl)aminomethane
Properties
Safety Information
European Hazard Symbols
Irritant (Xi)Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
GHS Signal Word
Warning
Risk Statements
36/37/38
Safety Statements
26-36
RTECS
TY2900000
German water hazard class
2
GHS Precautionary statements
P261-P305+P351+P338
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Hazard statements
H315-H319-H335
MSDS Link
Product Information
Grade
puriss. p.a.
Cation Traces
Fe: ≤5 mg/kg
Impurities
≤0.5% water (Karl Fischer)
≤0.0005% heavy metals (as Pb)
Linear Formula
NH2C(CH2OH)3
Useful pH Range
7 - 9
Antion Traces
sulfate (SO42-): ≤5 mg/kg
chloride (Cl-): ≤5 mg/kg
Purity
≥99.5%
Ignition Residue
≤0.05% (as SO4)
Description
aminopeptidase substrate
Physical Property
Melting Point
168-171 °C
167-172 °C(lit.)
pH
10.3-10.8 (0.1 M)
p𝘒ₐ
8.1 (25°C)
Boiling Point
219-220 °C/10 mmHg(lit.)
Molecule Details
Other Notes
The pH values of all buffers are temperature- and concentration-dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution.For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.
Legal Information
Trizma is a registered trademark of Sigma-Aldrich Co. LLC
The pH values of all buffers are temperature- and concentration-dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution.For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.
Legal Information
Trizma is a registered trademark of Sigma-Aldrich Co. LLC
Molecular Spectra
No Data Available
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References
No Data Available
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