Substance
ID:357325
Names and Identifiers
IUPAC name
piperidine-1-carbaldehyde
IUPAC Traditional name
N-formylpiperidine
Synonyms
N-Carbaldehyde piperidine1-甲酰哌啶哌啶-1-甲醛1-FormylpiperidineNFPPiperidine-1-carboxaldehyde
Registration numbers
CAS Number
MDL Number
Beilstein Number
EC Number
Properties
Physical Property
Flash Point
215.6 °F
102 °C
Vapor Pressure
0.1 mmHg ( 25 °C)
Refractive Index
n20/D 1.484(lit.)
n20/D 1.485
Boiling Point
222 °C(lit.)
Density
1.019 g/mL at 25 °C(lit.)
Safety Information
Personal Protective Equipment
Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RID/ADR
UN 2810 6.1/PG 3
GHS Precautionary statements
P261-P280-P305+P351+P338-P312
Safety Statements
26-36/37
Packing Group
3
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Risk Statements
21/22-36/37/38
GHS Hazard statements
H302-H311-H315-H319-H335
RTECS
TN0380000
UN Number
2810
German water hazard class
3
MSDS Link
Hazard Class
6.1
European Hazard Symbols
Harmful (Xn)GHS Signal Word
Danger
Product Information
Empirical Formula (Hill Notation)
C6H11NO
Purity
≥99.0% (GC)
Grade
purum
Molecule Details
Other Notes
Used in formyl transfer to Grignard reagents7
Application
Reactant for:
• Direct amidation of azoles with formamides via metal-free C-H activation in the presence of tert-butyl perbenzoate1
• Vilsmeier-type reactions of pyrazoles with amides in the presence of phosphorous oxychloride2
• CO-free aminocarbonylation of N-substituted formamides with aryl iodides/bromides catalyzed by palladium acetate and Xantphos for synthesis of arylamides3
• Synthesis of alternating copolymers for organic photovoltaic applications4
• One-pot double functionalization of π-deficient heterocyclic lithium reagents5
• Synthesis of thermally stable piezofluorochromic aggregation-induced emission compounds6
Used in formyl transfer to Grignard reagents7
Application
Reactant for:
• Direct amidation of azoles with formamides via metal-free C-H activation in the presence of tert-butyl perbenzoate1
• Vilsmeier-type reactions of pyrazoles with amides in the presence of phosphorous oxychloride2
• CO-free aminocarbonylation of N-substituted formamides with aryl iodides/bromides catalyzed by palladium acetate and Xantphos for synthesis of arylamides3
• Synthesis of alternating copolymers for organic photovoltaic applications4
• One-pot double functionalization of π-deficient heterocyclic lithium reagents5
• Synthesis of thermally stable piezofluorochromic aggregation-induced emission compounds6
Molecular Spectra
No Data Available
Click here to submit data
References
No Data Available
Click here to submit data