Substance
ID:353122
Names and Identifiers
IUPAC name
3,4-dichloro-1H-isochromen-1-one
Synonyms
3,4-DCI3,4-Dichloroisocoumarin3,4-Dichloro-2-benzopyran-1-one
IUPAC Traditional name
3,4-dichloroisocoumarin
Properties
Product Information
Empirical Formula (Hill Notation)
C9H4Cl2O2
Purity
≥99.0% (TLC)
Safety Information
RID/ADR
UN 2811 6.1/PG 3
UN Number
2811
Packing Group
3
German water hazard class
3
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Risk Statements
25-36/37/38
Personal Protective Equipment
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Hazard Class
6.1
GHS Signal Word
Danger
GHS Precautionary statements
P261-P301+P310-P305+P351+P338
European Hazard Symbols
Toxic (T)Storage Temperature
2-8°C
GHS Hazard statements
H301-H315-H319-H335
Safety Statements
26-36
MSDS Link
Molecule Details
Other Notes
Effective concentration 5-100 μM.
Inhibitor of serine proteases1; Inhibition of porcine pancreatic elastase2
Quantity
Half-life = 20 min at pH 7.5.
Substrates
Serine protease inhibitor. Active towards a wide range of serine proteases including granzymes. Not active toward β-lactamases.
Biochem/physiol Actions
Inhibitor of serine proteases1 and porcine pancreatic elastase2. Treatment of proteasomes leads to rapid inactivation of chymotrypsin-like activity and slower inactivation of other proteases.3
Effective concentration 5-100 μM.
Inhibitor of serine proteases1; Inhibition of porcine pancreatic elastase2
Quantity
Half-life = 20 min at pH 7.5.
Substrates
Serine protease inhibitor. Active towards a wide range of serine proteases including granzymes. Not active toward β-lactamases.
Biochem/physiol Actions
Inhibitor of serine proteases1 and porcine pancreatic elastase2. Treatment of proteasomes leads to rapid inactivation of chymotrypsin-like activity and slower inactivation of other proteases.3
Molecular Spectra
No Data Available
Click here to submit data
References
No Data Available
Click here to submit data