Substance
ID:351987
Names and Identifiers
IUPAC Traditional name
nicotinamide
IUPAC name
pyridine-3-carboxamide
Synonyms
Nicotinic acid amidePyridine-3-carboxylic acid amide维生素 B3烟碱酰胺烟酰胺维生素 PPNicotinamide尼克酰胺吡啶-3-甲酰胺niacinamideVitamin PPVitamin B3
Registration numbers
CAS Number
MDL Number
Beilstein Number
EC Number
PubChem SID
Properties
Product Information
Cation Traces
Ca: ≤10 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Fe: ≤5 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Na: ≤50 mg/kg
Cu: ≤5 mg/kg
Zn: ≤5 mg/kg
Mn: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Antion Traces
chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg
Ignition Residue
≤0.2%
Empirical Formula (Hill Notation)
C6H6N2O
Loss on Drying
≤0.2% loss on drying, 20 °C (HV)
Purity
≥99.5% (HPLC)
Pharmacology Properties
Gene Information
human ... PARP1(142), SIRT2(22933)
Safety Information
GHS Precautionary statements
P261-P305+P351+P338
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
European Hazard Symbols
Irritant (Xi)MSDS Link
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Safety Statements
26-36
GHS Signal Word
Warning
Risk Statements
36/37/38
German water hazard class
1
RTECS
QS3675000
GHS Hazard statements
H315-H319-H335
Physical Property
Flash Point
150 °C
302 °F
Melting Point
128-131 °C
128-131 °C(lit.)
Molecule Details
Other Notes
Coenzymes and Cofactors, vol. 2: Pyridine Nucleotide Coenzymes1,2
Biochem/physiol Actions
Nicotinamide (Niacinamide) (Nam) is a building block (active component) of coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phopshate (NADP). Nicotinamide may be used as a substrate of nicotinamide phosphoribosyltransferase (NAMPT, EC 2.4.2.12), the rate-limiting enzyme for NAD(+) biosynthesis and an important signaling molecule.
Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor
Coenzymes and Cofactors, vol. 2: Pyridine Nucleotide Coenzymes1,2
Biochem/physiol Actions
Nicotinamide (Niacinamide) (Nam) is a building block (active component) of coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phopshate (NADP). Nicotinamide may be used as a substrate of nicotinamide phosphoribosyltransferase (NAMPT, EC 2.4.2.12), the rate-limiting enzyme for NAD(+) biosynthesis and an important signaling molecule.
Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor
Molecular Spectra
No Data Available
Click here to submit data
References
No Data Available
Click here to submit data