An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake. [PubChem]
Research Area: Neurological Disease Biological Activity: Nicotinamide(Niacinamide) is a water-soluble vitamin and is part of the vitamin B group. Nicotinic acid, also known as niacin, is converted to nicotinamide in vivo, and, though the two are identical in their vitamin functions, nicotinamide does not have the same pharmacologic and toxic effects of niacin, which occur incidental to niacin’s conversion. [1]
Application Used as a cofactor for certain enzymes 包装 1 kg in poly bottle 100, 500 g in poly bottle Biochem/physiol Actions Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor
Other Notes Coenzymes and Cofactors, vol. 2: Pyridine Nucleotide Coenzymes1,2 Biochem/physiol Actions Nicotinamide (Niacinamide) (Nam) is a building block (active component) of coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phopshate (NADP). Nicotinamide may be used as a substrate of nicotinamide phosphoribosyltransferase (NAMPT, EC 2.4.2.12), the rate-limiting enzyme for NAD(+) biosynthesis and an important signaling molecule. Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor