Substance
ID:351766
Names and Identifiers
IUPAC name
2-amino-2-(hydroxymethyl)propane-1,3-diol
IUPAC Traditional name
tris buffer
Synonyms
2-Amino-2-(hydroxymethyl)-1,3-propanediolTrometamolTHAMTris base2-氨基-2-(羟甲基)-1,3-丙二醇Tris 碱氨基丁三醇三羟甲基氨基甲烷Trizma® baseTrizma® 碱Tris(hydroxymethyl)aminomethane
Registration numbers
CAS Number
MDL Number
EC Number
Beilstein Number
PubChem SID
Properties
Product Information
Cation Traces
Mg: ≤5 mg/kg
K: ≤50 mg/kg
Pb: ≤5 mg/kg
Co: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤50 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Fe: ≤5 mg/kg
Cr: ≤5 mg/kg
Ni: ≤5 mg/kg
Zn: ≤5 mg/kg
Cu: ≤5 mg/kg
Purity
≥99.7% (T)
Grade
puriss. p.a.
Ignition Residue
≤0.01% (as SO4)
Linear Formula
NH2C(CH2OH)3
Antion Traces
chloride (Cl-): ≤5 mg/kg
sulfate (SO42-): ≤5 mg/kg
Useful pH Range
7 - 9
Description
aminopeptidase substrate
λ
10 % in H2O
Physical Property
Boiling Point
219-220 °C/10 mmHg(lit.)
Melting Point
168-172 °C
167-172 °C(lit.)
Absorption Wavelength
λ: 260 nm Amax: ≤0.05
λ: 280 nm Amax: ≤0.04
λ: 430 nm Amax: ≤0.01
λ: 230 nm Amax: ≤0.6
p𝘒ₐ
8.1 (25°C)
pH
10.5-11.5 (25 °C, 10% in H2O)
Safety Information
Risk Statements
36/37/38
European Hazard Symbols
Irritant (Xi)GHS Hazard statements
H315-H319-H335
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements
P261-P305+P351+P338
RTECS
TY2900000
GHS Signal Word
Warning
Safety Statements
26-36
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
MSDS Link
German water hazard class
2
Molecule Details
Other Notes
Easily compare specifications for Trizma products with the Trizma specification table.
The pH values of all buffers are temperature- and concentration-dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution.For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.
Legal Information
Trizma is a registered trademark of Sigma-Aldrich Co. LLC
Easily compare specifications for Trizma products with the Trizma specification table.
The pH values of all buffers are temperature- and concentration-dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution.For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.
Legal Information
Trizma is a registered trademark of Sigma-Aldrich Co. LLC
Molecular Spectra
No Data Available
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References
No Data Available
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