Substance
ID:350128
Names and Identifiers
IUPAC Traditional name
amoxapine
Synonyms
Amoxapine2-Chloro-11-(1-piperazinyl)dibenz[b,f][1,4]oxazepine
IUPAC name
13-chloro-10-(piperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaene
Properties
Pharmacology Properties
Gene Information
human ... HTR2A(3356), HTR2B(3357), HTR2C(3358)
Safety Information
German water hazard class
3
GHS Signal Word
Warning
European Hazard Symbols
Harmful (Xn)MSDS Link
Risk Statements
22
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Safety Statements
36
GHS Hazard statements
H302
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
RTECS
HQ4025500
Physical Property
Solubility
methanol: soluble
Product Information
Empirical Formula (Hill Notation)
C17H16ClN3O
Molecule Details
Biochem/physiol Actions
Tricyclic antidepressant; inhibits uptake of norepinephrine; inhibits 5-HT2 serotonergic receptors.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. A129.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
Tricyclic antidepressant; inhibits uptake of norepinephrine; inhibits 5-HT2 serotonergic receptors.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. A129.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
Molecular Spectra
No Data Available
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References
No Data Available
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