Substance
ID:349968
Names and Identifiers
IUPAC name
2-amino-2-(hydroxymethyl)propane-1,3-diol
IUPAC Traditional name
tris buffer
Synonyms
2-Amino-2-(hydroxymethyl)-1,3-propanediolTrometamolTHAMTris base2-氨基-2-(羟甲基)-1,3-丙二醇Tris 碱氨基丁三醇三羟甲基氨基甲烷Trizma® baseTrizma® 碱Tris(hydroxymethyl)aminomethane
Registration numbers
CAS Number
MDL Number
EC Number
Beilstein Number
PubChem SID
Properties
Product Information
Quality Level
ELITE
Description
aminopeptidase substrate
Useful pH Range
7 - 9
Linear Formula
NH2C(CH2OH)3
Purity
≥99.9% (titration)
Safety Information
GHS Precautionary statements
P261-P305+P351+P338
German water hazard class
2
GHS Signal Word
Warning
European Hazard Symbols
Irritant (Xi)GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Hazard statements
H315-H319-H335
Safety Statements
26-36
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
RTECS
TY2900000
Risk Statements
36/37/38
MSDS Link
Physical Property
p𝘒ₐ
8.1 (25°C)
Apperance
yellow tan crystalline
Melting Point
167-172 °C(lit.)
Boiling Point
219-220 °C/10 mmHg(lit.)
Molecule Details
Analysis Note
Not pyrogen tested. Certificates of analysis are available with lot specific information.
Other Notes
The pH values of all buffers are temperature- and concentration-dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution.For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.
Packaging
Meets all specifications for T1503. For biotechnology, diagnostics or manufacturing use. Please inquire for commercial quantities.
Legal Information
Trizma is a registered trademark of Sigma-Aldrich Co. LLC
Not pyrogen tested. Certificates of analysis are available with lot specific information.
Other Notes
The pH values of all buffers are temperature- and concentration-dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution.For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.
Packaging
Meets all specifications for T1503. For biotechnology, diagnostics or manufacturing use. Please inquire for commercial quantities.
Legal Information
Trizma is a registered trademark of Sigma-Aldrich Co. LLC
Molecular Spectra
No Data Available
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References
No Data Available
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