Substance
ID:349965
Names and Identifiers
IUPAC name
2-amino-2-(hydroxymethyl)propane-1,3-diol
IUPAC Traditional name
tris buffer
Synonyms
2-Amino-2-(hydroxymethyl)-1,3-propanediolTrometamolTHAMTris base2-氨基-2-(羟甲基)-1,3-丙二醇Tris 碱氨基丁三醇三羟甲基氨基甲烷Tris(hydroxymethyl)aminomethaneTrizma® 碱Sigma 7-9®Trizma® base
Registration numbers
CAS Number
MDL Number
EC Number
Beilstein Number
PubChem SID
Properties
Product Information
abs.
A40%/290 ≤0.4
Purity
≥99% (titration)
Useful pH Range
7 - 9
Description
aminopeptidase substrate
Impurities
≤0.5% water (Karl Fischer)
Linear Formula
NH2C(CH2OH)3
Cation Traces
heavy metals (as Pb): ≤5 ppm
Safety Information
GHS Precautionary statements
P261-P305+P351+P338
German water hazard class
2
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
RTECS
TY2900000
Safety Statements
26-36
GHS Signal Word
Warning
GHS Hazard statements
H315-H319-H335
European Hazard Symbols
Irritant (Xi)MSDS Link
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Risk Statements
36/37/38
Physical Property
Apperance
white to off-white crystalline
p𝘒ₐ
8.1 (25°C)
Boiling Point
219-220 °C/10 mmHg(lit.)
Melting Point
167-172 °C(lit.)
Molecule Details
General description
A 40% (w/w) solution in water is clear, colorless to faint yellow
Other Notes
Easily compare specifications for Trizma products with the Trizma specification table.
The pH values of all buffers are temperature- and concentration-dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution.For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.
Legal Information
Sigma 7-9 is a registered trademark of Sigma-Aldrich Co. LLC
Trizma is a registered trademark of Sigma-Aldrich Co. LLC
A 40% (w/w) solution in water is clear, colorless to faint yellow
Other Notes
Easily compare specifications for Trizma products with the Trizma specification table.
The pH values of all buffers are temperature- and concentration-dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution.For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.
Legal Information
Sigma 7-9 is a registered trademark of Sigma-Aldrich Co. LLC
Trizma is a registered trademark of Sigma-Aldrich Co. LLC
Molecular Spectra
No Data Available
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References
No Data Available
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