Substance
ID:347568
Names and Identifiers
IUPAC name
2-amino-2-(hydroxymethyl)propane-1,3-diol
IUPAC Traditional name
tris buffer
Synonyms
2-Amino-2-(hydroxymethyl)-1,3-propanediolTrometamolTHAMTris base2-氨基-2-(羟甲基)-1,3-丙二醇Tris 碱氨基丁三醇三羟甲基氨基甲烷Trizma® baseTrizma® 碱Tris(hydroxymethyl)aminomethane
Properties
Product Information
abs.
A40%/290 ≤0.05
Purity
≥99.9% (titration)
Description
aminopeptidase substrate
Linear Formula
NH2C(CH2OH)3
pH Range
7.0 - 9.2
Useful pH Range
7 - 9
Cation Traces
heavy metals (as Pb): ≤2 ppm
Impurities
≤0.2% water (Karl Fischer)
Suitability
cell culture tested
Safety Information
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Precautionary statements
P261-P305+P351+P338
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
GHS Signal Word
Warning
GHS Hazard statements
H315-H319-H335
Safety Statements
26-36
European Hazard Symbols
Irritant (Xi)RTECS
TY2900000
Risk Statements
36/37/38
MSDS Link
German water hazard class
2
Physical Property
Boiling Point
219-220 °C/10 mmHg(lit.)
Melting Point
167-172 °C(lit.)
p𝘒ₐ
8.1 (25°C)
Apperance
white crystalline
Solubility
: soluble40 % (w/w), clear, colorless
Molecule Details
Other Notes
The pH values of all buffers are temperature- and concentration-dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution.For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.
Legal Information
Trizma is a registered trademark of Sigma-Aldrich Co. LLC
The pH values of all buffers are temperature- and concentration-dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution.For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.
Legal Information
Trizma is a registered trademark of Sigma-Aldrich Co. LLC
Molecular Spectra
No Data Available
Click here to submit data
References
No Data Available
Click here to submit data