Substance

ID:341807

Names and Identifiers
IUPAC Traditional name
benzyl chloroformate
IUPAC name
benzyl chloroformate
Synonyms
苯甲氧基甲酰氯Carbobenzoxy chlorideZ-Chloride苯甲氧羰酰氯Benzyl chloroformate氯甲酸苄酯
Registration numbers
CAS Number
MDL Number
PubChem SID
Beilstein Number
Properties
Safety Information
European Hazard Symbols
Nature polluting Nature polluting (N)
Toxic Toxic (T)
GHS Pictograms
GHS09
Hazardous to the aquatic environment
Acute hazard, category1
Chronic hazard, categories 1,2
GHS07
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS08
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
GHS05
Corrosive to metals, category 1
Skin corrosion, categories 1A,1B,1C
Serious eye damage, category 1
Storage Temperature
2-8°C
GHS Signal Word
Danger
Risk Statements
45-34-37-50/53
Packing Group
1
German water hazard class
3
Hazard Class
8
Safety Statements
53-26-36/37/39-45-61
UN Number
1739
MSDS Link
RID/ADR
UN 1739 8/PG 1
GHS Precautionary statements
P201-P261-P273-P280-P305+P351+P338-P310
GHS Hazard statements
H314-H335-H350-H410
Product Information
Purity
95%
Grade
technical grade
Linear Formula
ClCO2CH2C6H5
Physical Property
Refractive Index
n20/D 1.519(lit.)
Vapor Pressure
1.39 psi ( 20 °C)
Boiling Point
103 °C/20 mmHg(lit.)
Flash Point
197.6 °F
92 °C
Vapor Density
1 (vs air)
Density
1.195 g/mL at 25 °C(lit.)
Molecule Details
Application
Cbz-protected anilines were prepared directly from aromatic carboxylic acids, sodium azide and Cbz-Cl.1 Also used in a recently reported 3-step synthesis of 1,2,4-oxadiazoles.2
Protecting reagent in peptide synthesis.
Useful for the introduction of the benzyloxycarbonyl(Cbz,Z) protecting group
Packaging
100 g in Sure/Seal™
2.5 kg in Sure/Seal™
5 g in glass bottle
Molecular Spectra
No Data Available
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References
No Data Available
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