CAS 501-53-1|Benzyl chloroformate 95%|benzyl chloroformate|Benzyl carbonochloridoate|benzyl chloroformate|Benzyl chloroformate|benzyl carbonochloridate|Chloroformic acid benzyl ester|Carbobenzoxy ch...

InChI=1S/C8H7ClO2/c9-8(10)11-6-7-4-2-1-3-5-7/h1-5H,6H2

HSDAJNMJOMSNEV-UHFFFAOYSA-N

H Acceptors

H Donor

LogD (pH = 5.5)

2.6537483

LogD (pH = 7.4)

2.6537483

Log P

2.6537483

Molar Refractivity

42.7384

Polarizability

16.667994

Polar Surface Area

26.3

Rotatable Bonds

Lipinski's Rule of Five

true

Benzyl chloroformate 95%Benzyl carbonochloridoateBenzyl chloroformatebenzyl carbonochloridateChloroformic acid benzyl esterCarbobenzoxy chloride氯甲酸苄酯溶液苯甲氧羰酰氯苯甲氧基甲酰氯氯甲酸苄酯Z-ChlorideBenzyl chloroformate solutionBenzyl chloroformate

IUPAC Traditional name

benzyl chloroformate

Corrosive/Moisture Sensitive/Store at -20°C

Moisture Sensitive

R34,R50/53

45-34-37-50/53

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119938

Application
Cbz-protected anilines were prepared directly from aromatic carboxylic acids, sodium azide and Cbz-Cl.1 Also used in a recently reported 3-step synthesis of 1,2,4-oxadiazoles.2
Protecting reagent in peptide synthesis.
Useful for the introduction of the benzyloxycarbonyl(Cbz,Z) protecting group
Packaging
100 g in Sure/Seal™
2.5 kg in Sure/Seal™
5 g in glass bottle

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Names and Identifiers

Synonyms

IUPAC Traditional name

benzyl chloroformate

IUPAC name

benzyl chloroformate

Registration numbers

MDL Number

CAS Number

Chemspider ID

PubChem CID

Wikipedia Title

PubChem SID

Beilstein Number

EC Number

Merck Index

Molecule Details

119938

References

PubChem Literature

No Data Available

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Bioactivity

PubChem BioAssay

45-63-11-34-37-48/20-50/53-65-67

European Hazard Symbols

Nature polluting (N)

Corrosive (C)

Harmful (Xn)

Toxic (T)

Flammable (F)

EU Index

607-064-00-4

Safety Statements

S1/2,S26,S45,S60,S61

53-26-36/37/39-45-61

53-26-36/37/39-45-61-62

26-45-60-61

Storage Temperature

2-8°C

GHS Pictograms

Acute toxicity (oral, dermal, inhalation), category 4

Skin irritation, category 2

Eye irritation, category 2

Skin sensitisation, category 1

Specific Target Organ Toxicity – Single exposure, category 3

Respiratory sensitization, category 1

Germ cell mutagenicity, categories 1A,1B,2

Carcinogenicity, categories 1A,1B,2

Reproductive toxicity, categories 1A,1B,2

Specific Target Organ Toxicity – Single exposure, categories 1,2

Specific Target Organ Toxicity – Repeated exposure, categories 1,2

Aspiration Hazard, category 1

Hazardous to the aquatic environment

Acute hazard, category1

Chronic hazard, categories 1,2

Corrosive to metals, category 1

Skin corrosion, categories 1A,1B,1C

Serious eye damage, category 1

Flammable gases, category 1

Flammable aerosols, categories 1,2

Flammable liquids, categories 1,2,3

Self-reactive substances and mixtures, Types B,C,D,E,F

Pyrophoric liquids, category 1

Pyrophoric solids, category 1

Self-heating substances and mixtures

Substances and mixtures, which in contact with water, emit flammable gases, categories 1,2,3

Organic peroxides, Types B,C,D,E,F

GHS Precautionary statements

P201-P261-P273-P280-P305+P351+P338-P310

P201-P210-P261-P273-P280-P301+P310

P280-P273-P305+P351+P338-P309-P310-P501A

Hazard Class

MSDS Link

Download link

GHS Signal Word

Danger

RID/ADR

UN 1739 8/PG 1

UN 2924 3/PG 2

UN Number

1739

2924

UN1739

GHS Hazard statements

H314-H335-H350-H410

H225-H304-H314-H335-H336-H350-H361d-H373-H410

H314-H318-H400-H410

Packing Group

German water hazard class

Personal Protective Equipment

Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

TSCA Listed

是

Molecule

ID:92311