Substance

ID:341504

Tris(hydroxymethyl)aminomethane

Names and Identifiers
IUPAC name
2-amino-2-(hydroxymethyl)propane-1,3-diol
IUPAC Traditional name
tris buffer
Synonyms
2-Amino-2-(hydroxymethyl)-1,3-propanediolTrometamolTHAMTris base2-氨基-2-(羟甲基)-1,3-丙二醇Tris 碱氨基丁三醇Tris(hydroxymethyl)aminomethane三(羟基甲基)氨基甲烷
Registration numbers
CAS Number
MDL Number
EC Number
Beilstein Number
Properties
Product Information
Purity
≥99.9%
Grade
ultrapure grade
Useful pH Range
7 - 9
Linear Formula
NH2C(CH2OH)3
Safety Information
Risk Statements
36/37/38
RTECS
TY2900000
German water hazard class
2
European Hazard Symbols
Irritant Irritant (Xi)
GHS Pictograms
GHS07
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Safety Statements
26-36
GHS Hazard statements
H315-H319-H335
MSDS Link
GHS Precautionary statements
P261-P305+P351+P338
GHS Signal Word
Warning
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Physical Property
Melting Point
167-172 °C(lit.)
Boiling Point
219-220 °C/10 mmHg(lit.)
p𝘒ₐ
8.1 (25°C)
Molecule Details
Frequently Asked Questions
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Application
Buffer and primary pH standard. pKa=8.3 at 20°C.1 Auxiliary material in pharmaceutical science.2,3
Packaging
1 kg in poly bottle
5 g in glass bottle
100, 500 g in poly bottle
5 kg in poly drum
Molecular Spectra
No Data Available
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References
No Data Available
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