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Substance
ID:184102
Structure
Similarity
Functional Group
Text
ID:53503
Chlorpromazine hydrochloride
Sigma Aldrich
ID: C8138
Names and Identifiers
IUPAC name
[3-(2-chloro-10H-phenothiazin-10-yl)propyl]dimethylamine hydrochloride
IUPAC Traditional name
chlorpromazine hydrochloride
Synonyms
2-氯-10-(3-二甲氨基丙基)吩噻嗪 盐酸盐
Chlorpromazine hydrochloride
CPZ
氯丙嗪 盐酸盐
氯普马嗪
Registration numbers
MDL Number
MFCD00012654
CAS Number
69-09-0
EC Number
200-701-3
Beilstein Number
3779989
PubChem SID
24277891
Properties
Safety Information
GHS Signal Word
Danger
Personal Protective Equipment
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
UN Number
2811
Hazard Class
6.1
GHS Hazard statements
H301
-
H330
GHS Precautionary statements
P260
-
P284
-
P301+
P310
-
P310
RID/ADR
UN 2811 6.1/PG 1
German water hazard class
3
RTECS
SO1750000
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
European Hazard Symbols
Highly toxic (T+)
Safety Statements
28
-
36/37
-
45
Risk Statements
25
-
26
Packing Group
1
Pharmacology Properties
Gene Information
human ... DRD2(1813), HRH1(3269)
Product Information
Purity
≥98% (TLC)
Molecule Details
Application
在血红蛋白和过氧化物酶的微量测定中替代联苯胺、邻联茴香胺和邻联甲苯胺。
Biochem/physiol Actions
吩噻嗪类抗精神病药;D2 多巴胺受体拮抗剂,H1 组胺受体拮抗剂;抑制钙调蛋白依赖性环核苷酸磷酸二酯酶和一氧化氮合成酶的活化。
氯丙嗪表现出对白血病细胞的细胞毒性和抗增殖活性,但是不会影响正常淋巴细胞的活力。
Molecular Spectra
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References
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