CAS 1628-89-3|Methyl pyridin-2-yl ether|2-methoxypyridine|2-methoxypyridine|2-Methoxypyridine 99%|2-methoxypyridine|2-Methoxypyridine|2-甲氧基吡啶|Methyl 2-pyridyl ether

Molecular Formula

C₆H₇NO

Molecular Mass

109.12588

Exact Mass

109.05276385

InChI

InChI=1S/C6H7NO/c1-8-6-4-2-3-5-7-6/h2-5H,1H3

InChIKey

IWTFOFMTUOBLHG-UHFFFAOYSA-N

Canonic Smiles

COc1ccccn1

Isomeric Smiles

n1c(cccc1)OC

JChem

H Acceptors

H Donor

LogD (pH = 5.5)

1.1911516

LogD (pH = 7.4)

1.1923444

Log P

1.1923597

Molar Refractivity

30.6778

Polarizability

11.948264

Polar Surface Area

22.12

Rotatable Bonds

Lipinski's Rule of Five

true

Academic Data

PubChem

74201

Synonyms

Methyl pyridin-2-yl ether2-Methoxypyridine 99%2-methoxypyridine2-Methoxypyridine2-甲氧基吡啶Methyl 2-pyridyl ether

IUPAC Traditional name

2-methoxypyridine

IUPAC name

2-methoxypyridine

MDL Number

Beilstein Number

CAS Number

PubChem SID

Storage Warning

Flammable/Irritant

Risk Statements

10-36/37/38

Packing Group

III

GHS Pictograms

Flammable gases, category 1

Flammable aerosols, categories 1,2

Flammable liquids, categories 1,2,3

Self-reactive substances and mixtures, Types B,C,D,E,F

Pyrophoric liquids, category 1

Pyrophoric solids, category 1

Self-heating substances and mixtures

Substances and mixtures, which in contact with water, emit flammable gases, categories 1,2,3

Organic peroxides, Types B,C,D,E,F

Acute toxicity (oral, dermal, inhalation), category 4

Skin irritation, category 2

Eye irritation, category 2

Skin sensitisation, category 1

Specific Target Organ Toxicity – Single exposure, category 3

H226-H315-H319-H335

1993

UN3271

Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

P261-P305+P351+P338

P210-P241-P303+P361+P353-P305+P351+P338-P405-P501A

UN 1993 3/PG 3

26-36

26-37

Physical Property

Product Information

No Data Available

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Sigma Aldrich

M25406

Packaging
25, 100 g in glass bottle

From Data Sources

• Can be metallated at the 3-position with LDA at -70^o: J. Org. Chem., 53, 1367 (1988). With the unimetal superbase complex formed from 2 mol of n-BuLi and I mol of 2-(Dimethylamino)ethanol, B23616, in hexane, products are obtained resulting from apparent metallation at the 6-position. A radical mechanism, rather than a true 6-metallation, has been proposed for this reaction: J. Chem. Soc., Perkin 1, 3071 (1997). Analogous results have been reported with 2-chloropyridine: Org. Lett., 2, 803 (2000).