Molecule

DB00336 

S1644 

Research Area: Infection
Biological Activity:
Nitrofurazone is a topical anti-infective agent with an IC50 of 22.83 ± 1.2 µM, and effective against gram-negative and gram-positive bacteria. (Rat LD50 = 590 mg/kg)[1] Nitrofurazone (NF) and its derivative, hydroxymethylnitrofurazone (NFOH), have presented antichagasic activity. In vitro cruzain inhibition tests were performed for both compounds, and the 50% inhibitory concentration (IC50) for NF and NFOH presented values of 22.83 ± 1.2 µM and 10.55 ± 0.81 µM, respectively. AM1 semi-empirical molecular modeling studies were performed to understand the activity of the compounds, corroborating the observed cruzain inhibitory activity. [2]

02155880 

(Nitrofurazone)

05216984 

MP Biomedicals Rare Chemical collection

Nitrofural 

73340 

Packaging
100, 500 g in poly bottle

31706 

Legal Information
VETRANAL is a trademark of Sigma-Aldrich Co. LLC

N493880 

Anti-infective (topical). Antimicrobial.