物质信息

ID:964

名称和标识
IUPAC标准名
methyl (1R,15S,17R,18R,19S,20S)-18-methoxy-17-(3,4,5-trimethoxybenzoyloxy)-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4,6,8-tetraene-19-carboxylate
别名
DeserpineDeserpidineDeserpidina [INN-Spanish]Deserpidinum [INN-Latin]DeresperineDesmethoxyreserpineDeserpidinDesepridine
商标名
AescinCanescineRecanescinRecanescineCanescinEnduronylHarmonylRaunorminRaunorminebeta-EscinRaunorineReserpidineTranquinil
IUPAC传统名
methyl (1R,15S,17R,18R,19S,20S)-18-methoxy-17-(3,4,5-trimethoxybenzoyloxy)-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4,6,8-tetraene-19-carboxylate
数据登录号
PubChem SID
PubChem CID
CAS号
化合物性质
理化性质
疏水性(logP)
3.3
描述信息
Drug Groups
approved
Description
Deserpidine is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive properties that has been used for the control of high blood pressure and for the relief of psychotic behavior.
Indication
For the treatment of hypertension.
Pharmacology
Deserpidine, an alkaloid of Rauwolfia canescens, is used as an antihypertensive. Rauwolfia alkaloids work by controlling nerve impulses along certain nerve pathways. As a result, they act on the heart and blood vessels to lower blood pressure.
Toxicity
Symptoms of overdose include dizziness or drowsiness (severe), flushing of skin, pinpoint pupils of eyes and slowed pulse.
Affected Organisms
Humans and other mammals
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参考文献
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