物质信息

ID:961

名称和标识
IUPAC标准名
ethyl 4-aminobenzoate
IUPAC传统名
benzocaine
商标名
Amben Ethyl EsterAnaesthan-SyngalaAnaesthesinAnaesthinAnesthesineNorcainNorcaineParathesinAnestezinAnesthesinAnesthoneBaby AnbesolIdenthesinKeloformEthoformHurricaineAethoformOra-JelParathesineSolu HOrthesinTopcaineAmericaineDermoplast
别名
Ethyl P-AminobenzoateP-Ethoxycarboxylic AnilineBenzocaineEthyl AminobenzoateEthyl P-AminophenylcarboxylateP-CarbethoxyanilineEthylester Kyseliny P-AminobenzooveP-Aminobenzoic Acid, Ethyl Ester
数据登录号
CAS号
PubChem CID
PubChem SID
化合物性质
理化性质
疏水性(logP)
1.6
溶解度
1310 mg/L
描述信息
Drug Groups
approved
Description
A surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. [PubChem]
Indication
For general use as a lubricant and topical anesthetic on esophagus, larynx, mouth, nasal cavity, rectum, respiratory tract or trachea, urinary tract, vagina. It is also used to suppress gag reflex.
Pharmacology
Benzocaine is a local anesthetic commonly used as a topical pain reliever. It is the active ingredient in many over-the-counter analgesic ointments. It is also indicated for general use as a lubricant and topical anesthetic on intratracheal catheters and pharyngeal and nasal airways to obtund the pharyngeal and tracheal reflexes; on nasogastric and endoscopic tubes; urinary catheters; laryngoscopes; proctoscopes; sigmoidoscopes and vaginal specula.
Toxicity
LD50=3040 mg/kg (rat, oral)
Affected Organisms
Humans and other mammals
External Links
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