物质信息

ID:73993

名称和标识
别名
Detrol LAKabi-2234Tolterodine tartrate Tolterodine tartrate PNU-200583E
IUPAC传统名
L-tartaric acid; tolterodine
IUPAC标准名
(2R,3R)-2,3-dihydroxybutanedioic acid; 2-[(1R)-3-[bis(propan-2-yl)amino]-1-phenylpropyl]-4-methylphenol
数据登录号
化合物性质
安全信息
保存条件
-20°C
产品相关信息
成盐信息
tartrate
描述信息
Biological Activity:
Tolterodine tartrate (Detrol LA) is a tartrate salt of tolterodine that is a competitive muscarinic receptor antagonist. Tolterodine tartrate (Detrol LA) is indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency and frequency. Both urinary bladder contraction and salivation are mediated via cholinergic muscarinic receptors. In the anesthetized cat, tolterodine tartrate (Detrol LA) shows a selectivity for the urinary bladder over salivary glands. [1][2]References on Tolterodine tartrate (Detrol LA)[] European Journal of Pharmacology , 1997 , 327 :195–207
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参考文献
• Rahimy M et al. Arzneimittelforschung. 2002; 52(12):890-5.