物质信息

ID:73788

名称和标识
IUPAC标准名
(2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
IUPAC传统名
ferulic acid
别名
Fumalic acidFerulic acid
数据登录号
CAS号
化合物性质
安全信息
保存条件
-20°C
产品相关信息
成盐信息
Free Base
描述信息
Research Area: Cardiovascular Disease , Neurological Disease
Biological Activity:
Fumalic acid(Ferulic acid) is a hydroxycinnamic acid and a type of organic compound found in the Ferula assafoetida L. or Ligusticum chuanxiong. It has many pharmacology functions, such as anti-blood platelet collection , ease pain better the alive of prostate , relax the blood vessel convulsion. Like many phenols, it is an antioxidant in the sense that it is reactive toward free radicals such as reactive oxygen species (ROS). ROS and free radicals are implicated in DNA damage, cancer, accelerated cell aging. Animal studies and in vitro studies suggest that ferulic acid may have direct antitumor activity against breast cancer and liver cancer. Ferulic acid may have pro-apoptotic effects in cancer cells, thereby leading to their destruction. Ferulic acid may be effective at preventing cancer induced by exposure to the carcinogenic compounds benzopyrene and 4-nitroquinoline 1-oxide. [1][2]
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参考文献
• Kampa M et al. Breast Cancer Res. 2004;6(2):R63-74.