物质信息
ID:737139
名称和标识
别名
TDA-1Tris(3,6-dioxaheptyl)amineTris[2-(2-methoxyethoxy)ethyl]amine三(3,6-二氧庚基)胺
IUPAC传统名
8-[2-(2-methoxyethoxy)ethyl]-2,5,11,14-tetraoxa-8-azapentadecane
IUPAC标准名
8-[2-(2-methoxyethoxy)ethyl]-2,5,11,14-tetraoxa-8-azapentadecane
化合物性质
安全信息
保存注意事项
Air Sensitive & Hygroscopic
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
危险公开号
36/38
GHS危险声明
H315-H319
GHS警示性声明
P280-P305+P351+P338-P302+P352-P321-P362-P332+P313
欧盟危险性物质标志
刺激性 (Xi)TSCA收录
是
安全公开号
26-37
产品相关信息
纯度
95%
理化性质
闪点
162°C(323°F)
密度
1.011
折射率
1.4486
沸点
163-171°C/1mm
熔点
<-100°C
描述信息
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分子图谱
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参考文献
• Acyclic solid-liquid phase-transfer catalyst (see Appendix 2).
• In studies of solvent-free SNAr reactions, TDA-1 was found to be the best catalyst: Synth. Commun., 20, 2855 (1990); Heterocycles, 32, 1947 (1991). In combination with CuCl, is also a useful catalyst in the Ullmann aryl ether synthesis: J. Org. Chem., 50, 3717 (1985). An improved N-arylation of amides utilizes a catalyst combination of CuCl and TDA-1 (5:1): Synthesis, 312 (1989).
• Forms isolable 2:1 complexes with Grignard reagents: Tetrahedron, 45, 171 (1989).
• Accelerates dehydrobromination of alkyl halides in the presence of KOH: Org. Synth. Coll., 9, 539 (1998). For use in the Wittig reaction, see Cyclopropyltriphenylphosphonium bromide, B25102.
• Has been used in a number of aromatic nucleophilic substitution reactions:
• For use in a stereospecific glycosylation reaction of a pyrimidine base, see: Helv. Chim. Acta, 71, 1573 (1988).
• Solubilizes salts of alkali metals and of transition metals, e.g. PdCl2, RuCl3 and RhCl3, allowing these to be used in hydrogenation reactions: Synth. Commun., 19, 2833 (1989).