物质信息
ID:736863
名称和标识
别名
3-羟基丙腈3-HydroxypropionitrileEthylene cyanohydrin2-Cyanoethanol
IUPAC标准名
3-hydroxypropanenitrile
IUPAC传统名
ethylene cyanohydrin
化合物性质
产品相关信息
纯度
98%
安全信息
欧盟危险性物质标志
刺激性 (Xi)GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
GHS危险声明
H315-H319-H335
危险公开号
36/37/38
安全公开号
26-37
TSCA收录
是
RTECS编号
MU5250000
GHS警示性声明
P261-P305+P351+P338-P302+P352-P321-P405-P501A
理化性质
闪点
128°C(262°F)
密度
1.041
折射率
1.4250
沸点
227-228°C
熔点
-46°C
描述信息
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分子图谱
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参考文献
• Protection of carboxylic acids as 2-cyanoethyl esters can be accomplished by DCC-DMAP coupling. The esters can be cleaved with TBAF in DMF-THF: Chem. Pharm. Bull., 42, 147 (1994), or Na2S in methanol: Chem. Pharm. Bull., 42, 1579 (1994).
• Precursor of 2-cyanoethyl 2,2,2-trichloroethyl phosphorochloridate, a reagent for the phosphorylation of nucleosides: Synthesis, 831 (1980); see 2,2,2-Trichloroethanol, L08163.
• Can also be used to protect the phosphate group, by condensation with 2,4,6-Triisopropylbenzenesulfonyl chloride, A11458: Chem. Pharm. Bull.,25, 2844 (1977), or DCC: J. Am. Chem. Soc., 83, 159 (1961). Cleavage can be effected with an amine: Tetrahedron Lett., 23, 5119 (1982), ammonia: J. Org. Chem., 59, 2482 (1994); Tetrahedron Lett., 35, 4311 (1994), or TBAF: Tetrahedron Lett., 1255 (1976).