Research Area: Infection
Biological Activity:
Rifapentine (Priftin) is an antibiotic compound used in the treatment of tuberculosis. Treatment begins in an intensive phase of twice-weekly dosing, followed by a maintenance phase of once-weekly dosing. Rifapentine (Priftin) is an antibiotic that kills the bacterium that causes tuberculosis, Mycobacterium tuberculosis. Rifapentine (Priftin) targets DNA-dependent RNA polymerase — proteins that are necessary for RNA synthesis and the production of proteins. This process is different in human (eukaryotic) cells and bacteria; rifamycins, like rifapentine, only affects this process in bacteria. [1]