物质信息
ID:734720
名称和标识
IUPAC标准名
trichloro-1,3,5-triazine
别名
2,4,6-Trichloro-1,3,5-triazineCyanuric chloride三聚氯氰TCT
IUPAC传统名
cyanuric chloride
化合物性质
理化性质
沸点
192-194°C
密度
1.920
闪点
>190°C(374°F)
熔点
145-149°C
安全信息
欧盟危险性物质标志
剧毒 (T+)危险公开号
14-22-26-34-43
保存注意事项
Moisture Sensitive
GHS危险品标识
腐蚀金属，类别1
腐蚀皮肤，类别1A，1B，1C
严重眼损伤，类别1
急性毒性（口服，皮肤接触，吸入），类别1,2,3
GHS警示性声明
P260-P303+P361+P353-P304+P340-P305+P351+P338-P320-P330-P405-P501A
联合国危险货物编号
UN2670
联合国危险货物包装类别(PG)
II
TSCA收录
是
安全公开号
1/2-26-28-36/37/39-45-46-63
RTECS编号
XZ1400000
联合国危险货物等级
8
GHS危险声明
H330-H302-H317-H314
产品相关信息
纯度
98%
描述信息
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分子图谱
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参考文献
• For use, in combination with DMSO, in a mild and efficient alternative to the Swern oxidation of alcohols to aldehydes or ketones, see: J. Org. Chem., 66,7907 (2001).
• Effects deoxygenation of diaryl sulfoxides. Alkyl sulfoxides undergo ɑ-chlorination, which can be avoided by using cyanuric fluoride: Synthesis, 221 (1980).
• For a brief feature on uses of the reagent in synthesis, see: Synlett, 2156 (2006).
• Reagent for dehydration of aldoximes: J. Chem. Soc., Chem. Commun., 1226 (1972), and primary carboxamides: Synthesis, 657 (1980) to nitriles. The Vilsmeier-type complex with DMF also converts aldoximes cleanly to nitriles; ketoximes undergo the Beckmann rearrangement at room temperature in high yield: J. Org. Chem., 67, 6272 (2002). The complex converts primary and secondary alcohols to alkyl chlorides in high yield; addition of NaBr affords mainly the alkyl bromide: Org. Lett., 4, 553 (2002); whereas with 4 eq. of LiF, primary alcohols are selectively formylated, providing a mild and convenient method for their protection: J. Org. Chem., 67, 5152 (2002).
• In the presence of triethylamine, carboxylic acids are converted to their acid chlorides, allowing in situ formation of esters, amides and peptides: Tetrahedron Lett., 20, 3037 (1979). Similarly, sulfonic acids are converted to sulfonyl chlorides: Tetrahedron Lett., 44, 1499 (2003). ω-Hydroxy acids are converted to their lactones: Tetrahedron Lett., 21, 1893 (1980). Mild reagent in ?-lactam synthesis: Synthesis, 209 (1981). Carboxylic acids, including N-Boc, -Fmoc and -Cbz amino acids have been converted to alcohols in good yield by activation with cyanuric chloride and N-methylmorpholine (NMM), followed by reduction with aqueous NaBH4: Tetrahedron Lett., 40, 4395 (1999). Hydroxamic acids can also be prepared in a simple one-flask method using hydroxylamine hydrochloride in the presennce of NMM and DMAP: Org. Lett., 5, 2715 (2003).