物质信息
ID:73462
名称和标识
别名
KAD 3213KMD 3213RapafloSilodosin(Rapaflo)
IUPAC传统名
1-(3-hydroxypropyl)-5-[2-({2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl}amino)propyl]-2,3-dihydroindole-7-carboxamide
IUPAC标准名
1-(3-hydroxypropyl)-5-[2-({2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl}amino)propyl]-2,3-dihydro-1H-indole-7-carboxamide
数据登录号
CAS号
化合物性质
产品相关信息
成盐信息
Free Base
安全信息
保存条件
-20°C
描述信息
Research Area: Endocrinology
Biological Activity:
Silodosin(Rapaflo) is an α1-adrenoceptor antagonist with high uroselectivity. It causes practically no orthostatic hypotension (in contrast to other α1 blockers). Since Silodosin is a highly selective inhibitor of the α1A adrenergic receptor, it causes practically no orthostatic hypotension (in contrast to other α1 blockers). On the other hand, the high selectivity seems to cause more problems with ejaculation. [1]
Biological Activity:
Silodosin(Rapaflo) is an α1-adrenoceptor antagonist with high uroselectivity. It causes practically no orthostatic hypotension (in contrast to other α1 blockers). Since Silodosin is a highly selective inhibitor of the α1A adrenergic receptor, it causes practically no orthostatic hypotension (in contrast to other α1 blockers). On the other hand, the high selectivity seems to cause more problems with ejaculation. [1]
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参考文献
• http://en.wikipedia.org/wiki/Silodosin