物质信息
ID:73156
名称和标识
别名
Emend)AprepitantMK-869L-754030
IUPAC传统名
@aprepitant
IUPAC标准名
3-{[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl}-4,5-dihydro-1H-1,2,4-triazol-5-one
数据登录号
CAS号
化合物性质
药理学性质
作用靶点
substance P
产品相关信息
成盐信息
Free Base
安全信息
保存条件
-20°C
理化性质
溶解度
DMSO
描述信息
Research Area: Neurological Disease
Biological Activity:
Aprepitant is an antiemetic chemical compound that belongs to a class of drugs called substance P antagonists (SPA). It mediates its effect by blocking the neurokinin 1 (NK1) receptor. Aprepitant is used for prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) and for prevention of postoperative nausea and vomiting.[1]References on Aprepitant (MK-0869)[1] http://en.wikipedia.org/wiki/Aprepitant, ,
Biological Activity:
Aprepitant is an antiemetic chemical compound that belongs to a class of drugs called substance P antagonists (SPA). It mediates its effect by blocking the neurokinin 1 (NK1) receptor. Aprepitant is used for prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) and for prevention of postoperative nausea and vomiting.[1]References on Aprepitant (MK-0869)[1] http://en.wikipedia.org/wiki/Aprepitant, ,
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参考文献
• http://www.search.com/reference/Aprepitant